Bis-tris methane
Names | |
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IUPAC name
2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol[1] | |
Other names
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Identifiers | |
2205275 | |
6976-37-0 | |
ChEBI | CHEBI:41250 |
ChemSpider | 73505 |
EC number | 230-237-7 |
4519 | |
| |
Jmol-3D images | Image |
MeSH | Bistris |
PubChem | 81462 |
RTECS number | TY2900000 |
| |
Properties | |
Molecular formula |
C8H19NO5 |
Molar mass | 209.24 g·mol−1 |
Appearance | White crystals |
Odor | Odourless |
Melting point | 102 °C (216 °F; 375 K) |
209.2 g L−1 (at 20 °C) | |
Acidity (pKa) | 6.46 |
Basicity (pKb) | 7.54 |
UV-vis (λmax) | 280 nm |
Absorbance | 0.15 |
Hazards | |
GHS pictograms | |
GHS signal word | WARNING |
H315, H319, H335 | |
P261, P305+351+338 | |
EU classification | Xi |
R-phrases | R36/37/38 |
S-phrases | S26, S36 |
NFPA 704 | |
Related compounds | |
Related alkanols |
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Related compounds |
Diethylhydroxylamine |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
verify (what is: / ?) | |
Infobox references | |
Bis-tris is an abbreviation of the trivial name (Bis(2-hydroxyethyl)-amino-tris(hydroxymethyl)-methane) for 2-[Bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)-1,3-propanediol. It is generally used as a buffering agent in biochemistry. Bis-tris is an organic tertiary amine with labile protons having a pKa of 6.46 at 25°C. It is an effective buffer between the pH 5.8 and 7.3.
See also
References
- ↑ "Bistris - Compound Summary". PubChem Compound. USA: National Center for Biotechnology Information. 23 June 2005. Identification. Retrieved 9 April 2012.