Bacillus clausii

Bacillus clausii
Scientific classification
Kingdom: Bacteria
Phylum: Firmicutes
Class: Bacilli
Order: Bacillales
Family: Bacillaceae
Genus: Bacillus
Species: B. clausii
Binomial name
Bacillus clausii
Nielsen et al. 1995

Bacillus clausii is a rod-shaped, Gram-positive, motile and spore-forming bacterium which lives in the soil. It is classified as probiotic; microrganisms that maintain a symbiotic relationship with the host organism.[1] It is currently being studied in respiratory infections[2] and some gastrointestinal disorders.[3] Bacillus clausii, has been found to produce antimicrobial substances that are active against gram positive bacteria including but not limited to Staphylococcus aureus, Enterococcus faecium, and Clostridium difficile.[4]

Genome structure

Bacillus clausii has relativelly small genome that contains 4.30 Mbp with 4,108 protein coding genes.[4]

References

  1. Urdaci MC, Bressollier P, Pinchuk I (July 2004). "Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities". J. Clin. Gastroenterol. 38 (6 Suppl): S86–90. doi:10.1097/01.mcg.0000128925.06662.69. PMID 15220667.
  2. Marseglia GL, Tosca M, Cirillo I et al. (March 2007). "Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study". Ther Clin Risk Manag 3 (1): 13–7. doi:10.2147/tcrm.2007.3.1.13. PMC 1936284. PMID 18360611.
  3. Gabrielli M, Lauritano EC, Scarpellini E et al. (May 2009). "Bacillus clausii as a treatment of small intestinal bacterial overgrowth". Am. J. Gastroenterol. 104 (5): 1327–8. doi:10.1038/ajg.2009.91. PMID 19352343.
  4. 4.0 4.1 Urdaci, MC.; Bressollier, P.; Pinchuk, I. (Jul 2004). "Bacillus clausii probiotic strains: antimicrobial and immunomodulatory activities.". J Clin Gastroenterol 38 (6 Suppl): S86–90. doi:10.1097/01.mcg.0000128925.06662.69. PMID 15220667.

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