BRD9

Bromodomain-containing protein 9 is a protein that in humans is encoded by the BRD9 gene. [1]

Structure and interaction

BRD9 contains a bromodomain. It is closely related to BRD7. BRD9 is present in some SWI/SNF ATPase remodeling complexes.[2]

Role in cancer

The BRD9 gene is frequently is present in variable copy number in lung cancer.[3]

Small molecule inhibition

Small molecules capable of binding to the bromodomain of BRD9 have been developed.[4][5][6]

See also

Bromodomain


References

  1. "Entrez Gene: Bromodomain containing 9".
  2. PMID 23644491 (PubMed)
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  3. PMID 18328944 (PubMed)
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  4. PMID 24313754 (PubMed)
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  5. PMID 25864491 (PubMed)
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  6. PMID 25856009 (PubMed)
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