BNIPL
| BCL2/adenovirus E1B 19kD interacting protein like | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | BNIPL ; BNIP-S; BNIPL-1; BNIPL-2; BNIPL1; BNIPL2; BNIPS; PP753 | ||||||||||||
| External IDs | OMIM: 611275 MGI: 2384749 HomoloGene: 15900 GeneCards: BNIPL Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 149428 | 171388 | |||||||||||
| Ensembl | ENSG00000163141 | ENSMUSG00000028115 | |||||||||||
| UniProt | Q7Z465 | Q99JU7 | |||||||||||
| RefSeq (mRNA) | NM_001159642 | NM_001168356 | |||||||||||
| RefSeq (protein) | NP_001153114 | NP_001161828 | |||||||||||
| Location (UCSC) | Chr 1: 151.01 – 151.02 Mb | Chr 3: 95.24 – 95.25 Mb | |||||||||||
| PubMed search | |||||||||||||
Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein is a protein that in humans is encoded by the BNIPL gene.[1][2][3]
Interactions
BNIPL has been shown to interact with Macrophage migration inhibitory factor,[1] GFER,[1] CDC42,[4] BCL2-like 1[4][5] and Bcl-2.[4][5]
References
- ↑ 1.0 1.1 1.2 Shen L, Hu J, Lu H, Wu M, Qin W, Wan D, Li YY, Gu J (Apr 2003). "The apoptosis-associated protein BNIPL interacts with two cell proliferation-related proteins, MIF and GFER". FEBS Lett 540 (1-3): 86–90. doi:10.1016/S0014-5793(03)00229-1. PMID 12681488.
- ↑ Zhou YT, Soh UJ, Shang X, Guy GR, Low BC (Feb 2002). "The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequence". J Biol Chem 277 (9): 7483–92. doi:10.1074/jbc.M109459200. PMID 11741952.
- ↑ "Entrez Gene: BNIPL BCL2/adenovirus E1B 19kD interacting protein like".
- ↑ 4.0 4.1 4.2 Qin, Wenxin; Hu Jian, Guo Minglei, Xu Jian, Li Jinjun, Yao Genfu, Zhou Xiaomei, Jiang Huiqiu, Zhang Pingping, Shen Li, Wan Dafang, Gu Jianren (Aug 2003). "BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis". Biochem. Biophys. Res. Commun. (United States) 308 (2): 379–85. doi:10.1016/S0006-291X(03)01387-1. ISSN 0006-291X. PMID 12901880.
- ↑ 5.0 5.1 Yasuda, M; Han J W; Dionne C A; Boyd J M; Chinnadurai G (Feb 1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Res. (UNITED STATES) 59 (3): 533–7. ISSN 0008-5472. PMID 9973195.
Further reading
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Qin W, Hu J, Guo M et al. (2003). "BNIPL-2, a novel homologue of BNIP-2, interacts with Bcl-2 and Cdc42GAP in apoptosis.". Biochem. Biophys. Res. Commun. 308 (2): 379–85. doi:10.1016/S0006-291X(03)01387-1. PMID 12901880.
- Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Xie L, Qin WX, He XH et al. (2004). "Differential gene expression in human hepatocellular carcinoma Hep3B cells induced by apoptosis-related gene BNIPL-2.". World J. Gastroenterol. 10 (9): 1286–91. PMID 15112343.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Xie L, Qin WX, Li JJ et al. (2005). "cDNA expression array analysis of gene expression in human hepatocarcinoma Hep3B cells induced by BNIPL-1.". Acta Biochim. Biophys. Sin. (Shanghai) 37 (9): 618–24. doi:10.1111/j.1745-7270.2005.00086.x. PMID 16143817.
- Kimura K, Wakamatsu A, Suzuki Y et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Gregory SG, Barlow KF, McLay KE et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
- Valencia CA, Cotten SW, Liu R (2007). "Cleavage of BNIP-2 and BNIP-XL by caspases.". Biochem. Biophys. Res. Commun. 364 (3): 495–501. doi:10.1016/j.bbrc.2007.10.018. PMID 17961507.