BAZ2A

Bromodomain adjacent to zinc finger domain, 2A

Available structures

Ortholog search: PDBe, RCSB

List of PDB id codes
4LZ2, 4Q6F, 4QBM

Identifiers

BAZ2A ; TIP5; WALp3

External IDs

OMIM: 605682 MGI: 2151152 HomoloGene: 8393 IUPHAR: 2721 GeneCards: BAZ2A Gene

Gene ontology
Molecular function	• DNA binding • RNA binding • protein binding • zinc ion binding • ligand-dependent nuclear receptor binding • lysine-acetylated histone binding
Cellular component	• chromatin silencing complex • nucleolus • rDNA heterochromatin
Biological process	• chromatin silencing at rDNA • DNA methylation • chromatin remodeling • transcription, DNA-templated • regulation of transcription, DNA-templated • histone deacetylation • histone H4-K20 methylation • histone H3-K9 methylation • heterochromatin assembly involved in chromatin silencing • histone H4 deacetylation
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000076108

ENSMUSG00000040054

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 12:
56.99 – 57.03 Mb

Chr 10:
128.09 – 128.13 Mb

PubMed search

Bromodomain adjacent to zinc finger domain protein 2A is a protein that in humans is encoded by the BAZ2A gene.^[1]^[2]^[3]

References

↑ Jones MH, Hamana N, Nezu J, Shimane M (Jan 2000). "A novel family of bromodomain genes". Genomics 63 (1): 40–5. doi:10.1006/geno.1999.6071. PMID 10662543.
↑ Strohner R, Nemeth A, Jansa P, Hofmann-Rohrer U, Santoro R, Längst G et al. (Sep 2001). "NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines". The EMBO Journal 20 (17): 4892–900. doi:10.1093/emboj/20.17.4892. PMC 125270. PMID 11532953. Vancouver style error (help)
↑ "Entrez Gene: BAZ2A bromodomain adjacent to zinc finger domain, 2A".

Further reading

Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N et al. (Apr 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research 4 (2): 141–50. doi:10.1093/dnares/4.2.141. PMID 9205841.
Zhou Y, Santoro R, Grummt I (Sep 2002). "The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription". The EMBO Journal 21 (17): 4632–40. doi:10.1093/emboj/cdf460. PMC 126197. PMID 12198165.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J et al. (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935. Vancouver style error (help)
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P et al. (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N et al. (2007). "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". Genome Biology 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMC 2374985. PMID 17672918.