Atevirdine
 | |
| Names | |
|---|---|
| IUPAC name
[4-[3-(ethylamino)pyridin-2-yl]piperazin-1-yl]-(5-methoxy-1H-indol-2-yl)methanone | |
| Identifiers | |
136816-75-6  | |
| ChEMBL | ChEMBL280527  |
| ChemSpider | 54835 |
| |
| Jmol-3D images | Image |
| PubChem | 60848 |
| |
| Properties | |
| C21H25N5O2 | |
| Molar mass | 379.46 g/mol |
| Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
| verify (what is: /?) | |
| Infobox references | |
Ateviridine is non-nucleoside reverse transcriptase inhibitor that has been studied for the treatment of HIV.[1]
Synthesis
References
- ↑ Morse GD, Reichman RC, Fischl MA et al. (January 2000). "Concentration-targeted phase I trials of atevirdine mesylate in patients with HIV infection: dosage requirements and pharmacokinetic studies. The ACTG 187 and 199 study teams". Antiviral Res. 45 (1): 47–58. doi:10.1016/S0166-3542(99)00073-X. PMID 10774589.
- ↑ D. L. Romero, Drugs Future 19, 9 (1995).
- ↑ Romero, D. L.; Morge, R. A.; Biles, C.; Berrios-Pena, N.; May, P. D.; Palmer, J. R.; Johnson, P. D.; Smith, H. W.; Busso, M.; Et. Al. (1994). "Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors". Journal of Medicinal Chemistry 37 (7): 999. doi:10.1021/jm00033a018.
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