Aquaphor

Aquaphor
Aquaphor Healing Ointment Logo
Product type Skin protectant ointment
Owner Beiersdorf AG
Introduced 1925
Website www.discoveraquaphor.com

Aquaphor is a brand of over the counter skin care ointments manufactured by Beiersdorf Inc., an affiliate of Beiersdorf AG. Aquaphor It is offered in 4 product ranges: There are two skin protectant ointments.[1] Aquaphor Original Ointment, used as a compounding agent [2][3] and Aquaphor Advanced Therapy Healing Ointment, sold in mass retail outlets. The other product ranges include: Aquaphor Lip Repair and Lip Repair + Protect SPF 30, and Aquaphor Baby.

Aquaphor has been available in the US market for over 90 years. In accordance with the FDA OTC Skin Protectant Monograph [4] Aquaphor, containing 41% petrolatum (active ingredient), temporarily protects minor cuts, scrapes, and burns; protects and helps relieve chapped or cracked skin and lips; helps protect from the drying effects of wind and cold weather.[5]

History

First US trademark for ″Aquaphor″, dated May 26, 1925

1925: Aquaphor was developed in the Beiersdorf Inc laboratories in the USA. It was trademarked that year by Herman A. Metz, president of Beiersdorf Inc at that time.

1929: Beiersdorf sold Aquaphor’s trade marks to Duke Laboratories in order to manufacture products in the country.[6]

1936: Aquaphor’s first product offering was sold to doctors, pharmacists and hospitals in 5 lb. containers.

1960: Aquaphor production was discontinued during World War II and restarted by Duke Laboratiories in 1960. 1 lb cans and 2 oz tubes were sold to medical professionals.[6]

1973: Beiersdorf repurchased all trademarks from Duke Laboratories.[6]

1982: Aquaphor tube was introduced and directly sold to consumers for the first time.

1991: A new formulation Aquaphor Advanced Therapy Healing Ointment was launched, an addition to the Aquaphor Original Ointment.

2003: Aquaphor Baby Healing Ointment & Gentle Wash were introduced.

2011: Aquaphor Lip Repair was introduced

2012: Aquaphor Lip Repair + Protect SPF 30 was launched and Aquaphor is launched globally by Beiersdorf affiliates in 25 other countries.

2013: Aquaphor achieved the Good Housekeeping Seal.[7]

Properties

Unlike Vaseline (100% petrolatum), which is occlusive, Aquaphor (41% petrolatum) forms a semi-occlusive barrier on the skin. This enables the transmission of water and oxygen, important in wound healing, and the formation of a protective moist healing environment.[8] Its other key ingredients (see below) absorb the skin’s natural wound exudates, keeping the wound moist to help promote healing.[9]

Aquaphor is a non-comedogenic ointment and does not contain any fragrances, preservatives, or dyes.[9] Aquaphor is used and recommended for minor post-operative wounds or defects by health care professionals.[10]

Key Ingredients

Petrolatum

Active ingredient and OTC skin protectant, petrolatum forms an occlusive barrier on the skin and helps retain moisture.[11]

Lanolin Alcohol

A subfraction of Lanolin (Wool Wax), a mixture of hydrocarbons that imparts emulsifying properties and provides emolliency (skin smoothing properties). Lanolin Alcohol is composed of Cholesterol, other sterols, and free fatty acids.[12] Moisturizers containing Cholesterol and fatty acid mixtures have been shown to provide skin benefits.[13]

Glycerin

A natural moisturizing factor (NMF) and humectant that attracts and binds moisture in the stratum corneum (outer-most layer of epidermis), helping to keep it hydrated. It is commonly used as an moisturizing agent in lotions, creams, and cosmetics.[14][15][15]

Panthenol

Also known as pro- Vitamin B5 , when applied topically, has humectant properties and conditions the skin.[16] [17]

Bisabolol

Derived from the Chamomile plant, bisabolol can have anti-inflammatory, anti-pruritic and healing effects in-vivo.[18] [19]

Events

Every year, New York City holds a triathlon in Manhattan. The annual triathlon in July 2012 and July 2013 was sponsored by Aquaphor and had approximately 3000 triathletes competing.[20][21]

References

  1. ↑ FDA OTC>"21 CFR Part 310 Drugs for Human Use". Retrieved 28 October 2014.
  2. ↑ UNC Eshelman School of Pharmacy >"The Pharmaceutics and Compounding Laboratory". Retrieved 4 November 2014.
  3. ↑ Pharmacist's Letter >"Non-Sterile Compounding for the Community Pharmacy: Topical Preparations and Oral Liquid Dosage Forms" 2012. Pharmacist's Letter. Retrieved 4 November 2014.
  4. ↑ FDA OTC>"21 CFR Part 310 Drugs for Human Use". Retrieved 28 October 2014.
  5. ↑ FDA OTC>"21 CFR Part 347 Skin Protectant". Retrieved 28 October 2014.
  6. ↑ 6.0 6.1 6.2 Jones, Geoffrey; Lubinski, Christina (2011). "Managing Political Risk in Global Business: Beiersdorf 1914-1990". Oxford University Press. pp. 21;25;31. Retrieved 28 October 2014.
  7. ↑ Good Housekeeping >"Good Housekeeping Seal". p. 12. Retrieved 28 October 2014.
  8. ↑ Field, Charles K; Kerstein, Morris D (1994). "Overview of Wound Healing in a Moist Environment". The American Journal of Surgery (Department of Surgery, Hahnemann University School of Medicine, Philadelphia, Pennsylvania) 167 (1A): 2–6.
  9. ↑ 9.0 9.1 Trookman, Nathan S; Rizer, Ronald L; Weber, Teresa (2011). "Treatment of minor wounds from dermatologic procedures: A comparison of three topical wound care ointments using a laser wound model". Journal of the American Academy of Dermatology (American Academy of Dermatology, Inc.) 64 (3): 8–15. doi:10.1016/j.jaad.2010.11.011. ISSN 0190-9622. PMID 21247665.
  10. ↑ Nijhawan, Rajiv I; Smith, Lauren A; Kavita, Mariwalla (2013). "The Use of Topical Emollients in Post-Operative Wound Care Among Mohs Surgeons". Dermatol Surg (Wiley Periodicals Inc.) 39 (8): 2–6. doi:10.1111/dsu.12245. PMID 23777421.
  11. ↑ FDA OTC>"21 CFR Part 347 Skin Protectant". Retrieved 28 October 2014.
  12. ↑ Loden, Marie; Barany, Ebba (2008). "Skin-identical Lipids Versus Petrolatum in the Treatment of Tape-stripped and Detergent-perturbed Human Skin". Acad Dermatol Venerol (Taylor & Francis) 80 (8): 412–415. ISSN 0001-5555. PMID 11243632.
  13. ↑ Buraczewska, I.; Berne, B.; Lindberg, M.; Torma, H.; Loden, M. (2007). "Changes in skin barrier function following long-term treatment with moisturizers, a randomized controlled trial". British Journal of Dermatology (British Association of Dermatologists) 156 (3): 492–498. doi:10.111/j.1356-2133.2006.07685. PMID 17300239. Retrieved 28 October 2014.
  14. ↑ Bjoerklund, Sebastian; Engblom, Johan; Sparr, Emma (2013). "Glycerol and urea can be used to increase skin permeability in reduced hydration conditions". European Journal of Pharmaceutical Science (Elsevier B.V.) 50 (5): 638–645. doi:10.1016/j.ejps.2013.04.022.
  15. ↑ 15.0 15.1 Fluhr, J.W.; Gloor, M.; Lehmann, L.; Lazzerini, S; Distante, F.; Berardeska, E. (1999). "Glycerol Accelerates Recovery of Barrier Function In Vivo". Acta Derm Venereol (Scandinavian University Press.) 79 (6): 418–421. doi:10.1080/000155599750009825. PMID 10598752.
  16. ↑ Ebner, Fritz; Heller, Andreas; Rippke, Frank; Tausch, Irene (2002). "Topical Use of Dexpanthenol in Skin Disorders". American Journal of Clinical Dermatology (Springer International Publishing .) 3 (6): 427–433. doi:10.2165/00128071-00005. ISSN 1175-0561. Retrieved 24 October 2014.
  17. ↑ Proksch, E.; Nissen, H.P. (2002). "Dexpanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritation". J Dermatology Treat (PubMed) 13 (4): 173–178. doi:10.1080/09546630212345674. PMID 19753737. Retrieved 27 October 2014.
  18. ↑ Kim, S.; Jung, E.; Kim, JH; Park, YH; Lee, J.; Park, J. (2011). "Inhibitory effects of (-)-α -bisabolol on LPS-induced inflammatory response in RAW264.7 macrophages". Food Chemical Toxicol (PubMed) 49 (10): 2580–2585. doi:10.1016/j.fct.2011.06.076. PMID 21771629. Retrieved 27 October 2014.
  19. ↑ Arenberger, P.; Arenbergerova, M.; Drozenova, H.; Hladikova, M; Holcova, S. (2011). "Effect of topical heparin and levomenol an atopic dermatitis: a randomized four-arm, placebo-controlled, double-blind clinical study". J Eur Acad Dermatol Venerol (PubMed) 25 (6): 688–694. doi:10.111/j.1468-3083.2010.03950. PMID 21214633. Retrieved 27 October 2014.
  20. ↑ Aquaphor>Wilburn, Glenn. "Thousands of athletes compete in Aquaphor NYC Triathlon". Fox NY. Retrieved 19 February 2013.
  21. ↑ Aquaphor>Carvajal, Kathy. "Aquaphor NYC Triathlon 2013". Fox NY. Retrieved 24 October 2014.

External links