Andy Brass

Andy Brass
Born Andrew M. Brass
Fields Bioinformatics
Institutions
Alma mater University of Edinburgh
Thesis Molecular dynamics simulations of fluorite structure crystals (1987)
Doctoral students
Website
www.manchester.ac.uk/research/andy.brass

Andrew M. Brass is a Professor of Bioinformatics at the University of Manchester in the School of Computer Science and Faculty of Life Sciences.[21][22][23][24][25]

Education

Brass was educated at the University of Edinburgh, receiving his PhD on Solid-state physics in 1987.[26]

Research

Following his PhD, Brass worked at McMaster University[27][28] in Canada on a NATO fellowship to study aspects of high-temperature superconductivity and strongly coupled electron systems. In 1990 he moved to the University of Manchester[29][30] to become a founding member of the bioinformatics group, where he has a wide range of projects in protein function prediction, gene expression analysis, intelligent integration,[31] automated curation,[32] and bioinformatics education.[33]

References

  1. ↑ Fisher, Paul Ryan (2009). Towards a systematic approach to the large-scale analysis of genotype-phenotype correlations (PhD thesis). University of Manchester.
  2. ↑ Noyes, H.; Brass, A.; Obara, I.; Anderson, S.; Archibald, A. L.; Bradley, D. G.; Fisher, P.; Freeman, A.; Gibson, J.; Gicheru, M.; Hall, L.; Hanotte, O.; Hulme, H.; McKeever, D.; Murray, C.; Oh, S. J.; Tate, C.; Smith, K.; Tapio, M.; Wambugu, J.; Williams, D. J.; Agaba, M.; Kemp, S. J. (2011). "Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection". Proceedings of the National Academy of Sciences 108 (22): 9304–9309. doi:10.1073/pnas.1013486108. PMC 3107286. PMID 21593421.
  3. ↑ Fisher, P.; Noyes, H.; Kemp, S.; Stevens, R.; Brass, A. (2009). "A Systematic Strategy for the Discovery of Candidate Genes Responsible for Phenotypic Variation". Cardiovascular Genomics. Methods in Molecular Biology 573. pp. 329–345. doi:10.1007/978-1-60761-247-6_18. ISBN 978-1-60761-246-9. PMID 19763936.
  4. ↑ Rennie, C.; Hulme, H.; Fisher, P.; Halp, L.; Agaba, M.; Noyes, H. A.; Kemp, S. J.; Brass, A. (2008). "A systematic, data-driven approach to the combined analysis of microarray and QTL data". Developments in biologicals. Developments in Biologicals 132: 293–299. doi:10.1159/000317174. ISBN 978-3-8055-8619-1. PMID 18817316.
  5. ↑ 5.0 5.1 Fisher, P.; Hedeler, C.; Wolstencroft, K.; Hulme, H.; Noyes, H.; Kemp, S.; Stevens, R.; Brass, A. (2007). "A systematic strategy for large-scale analysis of genotype phenotype correlations: Identification of candidate genes involved in African trypanosomiasis". Nucleic Acids Research 35 (16): 5625–5633. doi:10.1093/nar/gkm623. PMC 2018629. PMID 17709344.
  6. ↑ Han, Nam Shik (2013). Systematic approaches for modelling and visualising responses to perturbation of transcriptional regulatory networks (PhD thesis). University of Manchester.
  7. ↑ Ranandeh Kalankesh, Leila (2010). Exploring nature of the structured data in GP electronic patient records (PhD thesis). University of Manchester.
  8. ↑ Kalankesh, L. R.; Stevens, R.; Brass, A. (2012). "The language of gene ontology: A Zipf's law analysis". BMC Bioinformatics 13: 127. doi:10.1186/1471-2105-13-127. PMC 3473240. PMID 22676436.
  9. ↑ Mallon, Ann-Marie (2004). Comparative analysis of the mouse and human genomes (PhD thesis). University of Manchester.
  10. ↑ Morrison, Norman (2003). Microarray data analysis: a comparison of normalisation techniques and case study (PhD thesis). University of Manchester.
  11. ↑ Tate, Catriona Mary (2010). Effect of probe-target sequence mismatches on the results of microarray hybridisations: position-dependence, modelling and impact of evolutionary distance (PhD thesis). University of Manchester.
  12. ↑ Noyes, H.; Brass, A.; Obara, I.; Anderson, S.; Archibald, A. L.; Bradley, D. G.; Fisher, P.; Freeman, A.; Gibson, J.; Gicheru, M.; Hall, L.; Hanotte, O.; Hulme, H.; McKeever, D.; Murray, C.; Oh, S. J.; Tate, C.; Smith, K.; Tapio, M.; Wambugu, J.; Williams, D. J.; Agaba, M.; Kemp, S. J. (2011). "Genetic and expression analysis of cattle identifies candidate genes in pathways responding to Trypanosoma congolense infection". Proceedings of the National Academy of Sciences 108 (22): 9304–9309. doi:10.1073/pnas.1013486108. PMC 3107286. PMID 21593421.
  13. ↑ Tipney, Hannah Jane (2006). Bioinformatics as a tool to predict gene function in Williams-Beuren Syndrome (PhD thesis). University of Manchester.
  14. ↑ Hinsley, T. A.; Cunliffe, P.; Tipney, H. J.; Brass, A.; Tassabehji, M. (2009). "Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome". Protein Science 13 (10): 2588–2599. doi:10.1110/ps.04747604. PMC 2286546. PMID 15388857.
  15. ↑ Stevens, R. D.; Tipney, H. J.; Wroe, C. J.; Oinn, T. M.; Senger, M.; Lord, P. W.; Goble, C. A.; Brass, A.; Tassabehji, M. (2004). "Exploring Williams-Beuren syndrome using myGrid". Bioinformatics 20: i303–i310. doi:10.1093/bioinformatics/bth944. PMID 15262813.
  16. ↑ Tipney, H. J.; Hinsley, T. A.; Brass, A.; Metcalfe, K.; Donnai, D.; Tassabehji, M. (2004). "Isolation and characterisation of GTF2IRD2, a novel fusion gene and member of the TFII-I family of transcription factors, deleted in Williams–Beuren syndrome". European Journal of Human Genetics 12 (7): 551–560. doi:10.1038/sj.ejhg.5201174. PMID 15100712.
  17. ↑ Wolstencroft, Katherine Jane (2005). Ontological methods for structuring and managing protein family resources (PhD thesis). University of Manchester.
  18. ↑ Wolstencroft, K.; Lord, P.; Tabernero, L.; Brass, A.; Stevens, R. (2006). "Protein classification using ontology classification". Bioinformatics 22 (14): e530–e538. doi:10.1093/bioinformatics/btl208. PMID 16873517.
  19. ↑ Wolstencroft, K.; McEntire, R.; Stevens, R.; Tabernero, L.; Brass, A. (2004). "Constructing ontology-driven protein family databases". Bioinformatics 21 (8): 1685–1692. doi:10.1093/bioinformatics/bti158. PMID 15564301.
  20. ↑ Wolstencroft, K. J.; Stevens, R.; Tabernero, L.; Brass, A. (2004). "PhosphaBase: An ontology-driven database resource for protein phosphatases". Proteins: Structure, Function, and Bioinformatics 58 (2): 290–294. doi:10.1002/prot.20325. PMID 15558746.
  21. ↑ Andy Brass's publications indexed by Google Scholar, a free service provided by Google
  22. ↑ List of publications from Microsoft Academic Search
  23. ↑ Andy Brass's publications indexed by the DBLP Bibliography Server at the University of Trier
  24. ↑ Andy Brass's publications indexed by the Scopus bibliographic database, a service provided by Elsevier.
  25. ↑ Andy Brass from the ACM Portal
  26. ↑ Brass, Andrew (1987). Molecular dynamics simulations of fluorite structure crystals (PhD thesis). University of Edinburgh.
  27. ↑ Jensen, H.; Brass, A.; Berlinsky, A. (1988). "Lattice deformations and plastic flow through bottlenecks in a two-dimensional model for flux pinning in type-II superconductors". Physical Review Letters 60 (16): 1676–1679. doi:10.1103/PhysRevLett.60.1676. PMID 10038108.
  28. ↑ Jensen, H.; Brass, A.; Brechet, Y.; Berlinsky, A. (1988). "Current-voltage characteristics in a two-dimensional model for flux flow in type-II superconductors". Physical Review B 38 (13): 9235. doi:10.1103/PhysRevB.38.9235.
  29. ↑ Scott, J. E.; Cummings, C.; Brass, A.; Chen, Y. (1991). "Secondary and tertiary structures of hyaluronan in aqueous solution, investigated by rotary shadowing-electron microscopy and computer simulation. Hyaluronan is a very efficient network-forming polymer". The Biochemical journal. 274 ( Pt 3) (Pt 3): 699–705. PMC 1149968. PMID 2012600.
  30. ↑ Tuckwell, D. S.; Brass, A.; Humphries, M. J. (1992). "Homology modelling of integrin EF-hands. Evidence for widespread use of a conserved cation-binding site". The Biochemical journal. 285 ( Pt 1) (Pt 1): 325–331. PMC 1132784. PMID 1322124.
  31. ↑ Lord, P. W.; Stevens, R. D.; Brass, A.; Goble, C. A. (2003). "Investigating semantic similarity measures across the Gene Ontology: The relationship between sequence and annotation". Bioinformatics 19 (10): 1275–1283. doi:10.1093/bioinformatics/btg153. PMID 12835272.
  32. ↑ Taylor, C. F.; Paton, N. W.; Garwood, K. L.; Kirby, P. D.; Stead, D. A.; Yin, Z.; Deutsch, E. W.; Selway, L.; Walker, J.; Riba-Garcia, I.; Mohammed, S.; Deery, M. J.; Howard, J. A.; Dunkley, T.; Aebersold, R.; Kell, D. B.; Lilley, K. S.; Roepstorff, P.; Yates Jr, J. R.; Brass, A.; Brown, A. J. P.; Cash, P.; Gaskell, S. J.; Hubbard, S. J.; Oliver, S. G. (2003). "A systematic approach to modeling, capturing, and disseminating proteomics experimental data". Nature Biotechnology 21 (3): 247–254. doi:10.1038/nbt0303-247. PMID 12610571.
  33. ↑ Goble, C. A.; Stevens, R.; Ng, G.; Bechhofer, S.; Paton, N. W.; Baker, P. G.; Peim, M.; Brass, A. (2001). "Transparent access to multiple bioinformatics information sources". IBM Systems Journal 40 (2): 532–551. doi:10.1147/sj.402.0532.