Ampyrone
Ampyrone
![](../I/m/Ampyrone_structure.png) |
Names |
IUPAC name
4-Amino-2,3-dimethyl-1-phenyl-3-pyrazol-5-one |
Other names
solvapyrin A, aminoazophene, aminoantipyrene, metapyrazone |
Identifiers |
|
83-07-8 Y |
ChEBI |
CHEBI:59026 Y |
ChEMBL |
ChEMBL1165011 Y |
ChemSpider |
2066 Y |
InChI=1S/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3 YKey: RLFWWDJHLFCNIJ-UHFFFAOYSA-N YInChI=1/C11H13N3O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,12H2,1-2H3 Key: RLFWWDJHLFCNIJ-UHFFFAOYAT
|
Jmol-3D images |
Image |
PubChem |
2151 |
O=C2\C(=C(/N(N2c1ccccc1)C)C)N
|
UNII |
0M0B7474RA Y |
Properties |
Molecular formula |
C11H13N3O |
Molar mass |
203.24 g·mol−1 |
Density |
1.207g/cm3 |
Melting point |
106 to 110 °C (223 to 230 °F; 379 to 383 K) |
Boiling point |
309 °C (588 °F; 582 K) @760mmHg |
Hazards |
Flash point |
140.7 °C (285.3 °F; 413.8 K) |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) |
Y verify (what is: Y/ N?) |
Infobox references |
|
|
Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. Due to the risk of agranulocytosis its use as a drug is discouraged.[1] It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates liver microsomes and is also used to measure extracellular water.
References
Non-steroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA) |
---|
| Pyrazolones / Pyrazolidines | |
---|
| Salicylates | |
---|
| Acetic acid derivatives and related substances | |
---|
| Oxicams | |
---|
| Propionic acid derivatives (profens) | |
---|
| N-Arylanthranilic acids (fenamates) | |
---|
| Coxibs | |
---|
| Other | |
---|
| | | |
---|
| Description |
- Anatomy
- head
- neck
- arms
- chest and back
- diaphragm
- abdomen
- genital area
- legs
- Muscle tissue
- Physiology
|
---|
| Disease |
- Myopathy
- Soft tissue
- Connective tissue
- Congenital
- abdomen
- muscular dystrophy
- Neoplasms and cancer
- Injury
- Symptoms and signs
|
---|
| Treatment |
- Procedures
- Drugs
- anti-inflammatory
- muscle relaxants
|
---|
|
|
|
---|
| Opioids | |
---|
| Anilines | |
---|
| NSAIDs | |
---|
| Cannabinoids | |
---|
| Channelergics | |
---|
| Myorelaxants | |
---|
| Others | |
---|
|
| | |
---|
| Description |
- Anatomy
- meninges
- cortex
- association fibers
- commissural fibers
- lateral ventricles
- basal ganglia
- diencephalon
- mesencephalon
- pons
- cerebellum
- medulla
- spinal cord
- Physiology
- Development
|
---|
| Disease |
- Cerebral palsy
- Meningitis
- Demyelinating diseases
- Seizures and epilepsy
- Headache
- Stroke
- Sleep
- Congenital
- Injury
- Neoplasms and cancer
- Other
- Symptoms and signs
- head and neck
- eponymous
- lesions
- Tests
|
---|
| Treatment |
- Procedures
- Drugs
- general anesthetics
- analgesics
- addiction
- epilepsy
- cholinergics
- migraine
- Parkinson's
- vertigo
- other
|
---|
|
|