Aminometradine

Aminometradine
Systematic (IUPAC) name

6-Amino-3-ethyl-1-prop-2-enylpyrimidine-2,4-dione
Clinical data
Identifiers
CAS Registry Number	642-44-4
ATC code	None
PubChem	CID 12551
ChemSpider	12033^Y
UNII	PPM8SX5Q3V^Y
Chemical data
Formula	C₉H₁₃N₃O₂
Molecular mass	195.22 g/mol
SMILES O=C1N(/C(=C\C(=O)N1CC)N)C\C=C
InChI InChI=1S/C9H13N3O2/c1-3-5-12-7(10)6-8(13)11(4-2)9(12)14/h3,6H,1,4-5,10H2,2H3 ^Y Key:NGXUUAFYUCOICP-UHFFFAOYSA-N ^Y
Y (what is this?) (verify)

Aminometradine is a weak diuretic which was used to control oedema in those who suffered mild congestive heart failure.

Alkyl uracil derivatives have been known for some time to act as diuretic agents in experimental animals. The toxicity of these agents precluded their use in the clinic. Appropriate modification of the molecule, did, however yield diuretic agents in man.

Aminometradine

References