Aminocyclitol

The aminocyclitols are compounds related to cyclitols. They possess features of relative and absolute configuration that are characteristic of their class and have been extensively studied; but these features are not clearly displayed by general methods of stereochemical nomenclature, so that special methods of specifying their configuration are justified and have long been used. In other than stereochemical respects, their nomenclature should follow the general rules of organic chemistry.

The aminocyclitol family of natural products is a class of sugar-derived microbial secondary metabolites that demonstrate significant biological activities.

Aminocyclitols are a major component of aminoglycoside antibiotics.

Naturally occurring aminocyclitols

• Valienamine

References

1. http://www.chem.qmul.ac.uk/iupac/cyclitol/

2. Biosynthesis of unusual aminocyclitol-containing natural products. J Nat Prod. 2007 Aug;70(8):1384-91. Epub 2007 Jul 28.

3. Synthesis of aminocyclitol derivatives in the Open Access Beilstein Journal of Organic Chemistry.