Altoqualine
Names | |
---|---|
IUPAC name
(3S)-7-Amino-4,5,6-triethoxy-3-[(1R)-6,7,8-trimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]-3H-2-benzofuran-1-one | |
Other names
458 L | |
Identifiers | |
121029-11-6 | |
ChEMBL | ChEMBL2104645 |
ChemSpider | 2301104 |
| |
Jmol-3D images | Image |
PubChem | 3037346 |
| |
Properties | |
Molecular formula |
C27H36N2O8 |
Molar mass | 516.58 g·mol−1 |
Melting point | 144 °C (291 °F; 417 K)[1] |
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
Infobox references | |
Altoqualine is an isoquinoline once studied for its potential use as an antihistamine and antiallergic,[1][2][3] but it was never a marketed drug. It is an inhibitor of histidine decarboxylase.[2]
References
- ↑ 1.0 1.1 C.R. Ganellin, David J. Triggle (Nov 21, 1996). Dictionary of Pharmacological Agents, 1–2. CRC Press. p. 58.
- ↑ 2.0 2.1 Lallouette P; Mordelet-Dambrine M; Treize G; N'Guyen V T; Dubois A M; Parrot J L (1981). "Pharmacological approach of a new isoquinoline derivative (458 L)". Agents and actions 11 (1–2): 41–43. doi:10.1007/BF01991453. PMID 7195643.
- ↑ Bargnoux H; Kantelip J P; Bastide M; Duchene-Marullaz P; Boyer R; Lallouette P; Petit J; Berger J A (1990). "Pharmacokinetic study of a new benzyl-1 isoquinoline derivative (458 L) after oral administration in men". Therapie 45 (1): 7–11. PMID 1971461.