Aloxiprin

Aloxiprin

Systematic (IUPAC) name
aluminum 2-acetyloxybenzoate hydroxide
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	9014-67-9
ATC code	B01AC15 N02BA02
PubChem	CID 3032790
ChemSpider	2297682 Y
UNII	6QT214X4XU Y
KEGG	D07421 Y
Chemical data
Formula	C18H15O9
Molecular mass	402.288 g/mol
SMILES [Al+3].O=C(Oc1ccccc1C([O-])=O)C.[OH-].[O-]C(=O)c1ccccc1OC(=O)C
InChI InChI=1S/2C9H8O4.Al.H2O/c2*1-6(10)13-8-5-3-2-4-7(8)9(11)12;;/h2*2-5H,1H3,(H,11,12);;1H2/q;;+3;/p-3  Y Key:MANKSFVECICGLK-UHFFFAOYSA-K  Y
Y (what is this?)  (verify)

Aloxiprin (or aluminium acetylsalicylate) is a medical drug used for the treatment of pain and inflammation associated with muscular skeletal and joint disorders.^[1] It is used for its properties as an anti-inflammatory, antipyretic and analgesic drug.^[1] It is a chemical compound of aluminium hydroxide and aspirin.^[2][3]

Alternative names and combinations

• Palaprin Forte.^[4]
• Askit- A powder combination of aspirin, aloxiprin and caffeine.^[5]

Contraindications

• People with allergies to salicylates.
• People with gastrointestinal ulcers.
• People with liver or kidney damage.
• Pregnant women in the 3rd trimester.
• Women who are breastfeeding.
• Use with other salicylates.
• Use with NSAIDs.

References

1. ↑ 1.0 1.1 MIMS. "Aloxiprin". MIMS. Retrieved 16 April 2011. 
2. ↑ Encarta. "Aloxiprin". Encarta. Retrieved 16 April 2011. 
3. ↑ CUMMINGS AJ, MARTIN BK, WIGGINS LF (1963). "In vitro and in vivo properties of aloxiprin: a new aluminium derivative of acetylsalicylic acid". J. Pharm. Pharmacol. 15: 56–62. PMID 14024235. 
4. ↑ Geller J (1968). "A comparative trial of aloxiprin ('Palaprin Forte') and phenylbutazone ('Butazolidin')". The British journal of clinical practice 22 (9): 392–4. PMID 4876729. 
5. ↑ Net Doctor UK. "Askit Powders". Treatments for joint, muscle and bone conditions. Retrieved 16 April 2011. 

External links

• CTD's Aloxiprin page from the Comparative Toxicogenomics Database