Alkylhalidase
| alkylhalidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 3.8.1.1 | ||||||||
| CAS number | 9025-22-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, an alkylhalidase (EC 3.8.1.1) is an enzyme that catalyzes the chemical reaction
- bromochloromethane + H2O
formaldehyde + bromide + chloride
Thus, the two substrates of this enzyme are bromochloromethane and H2O, whereas its 3 products are formaldehyde, bromide, and chloride.
This enzyme belongs to the family of hydrolases, specifically those acting on halide bonds in carbon-halide compounds. The systematic name of this enzyme class is alkyl-halide halidohydrolase. Other names in common use include halogenase, haloalkane halidohydrolase, and haloalkane dehalogenase.
References
- Heppel LA and Porterfield VT (1948). "Enzymatic dehalogenation of certain brominated and chlorinated compounds" (PDF). J. Biol. Chem. 176 (2): 763–769. PMID 18889931.