Alafosfalin

Alafosfalin
Names

IUPAC name ((1R)-1-(((2S)-2-aminopropanoyl)amino]ethyl)phosphonic acid
Identifiers
CAS Registry Number	60668-24-8
ChemSpider	64964
InChI InChI=1S/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1 Key: BHAYDBSYOBONRV-IUYQGCFVSA-N InChI=1/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1 Key: BHAYDBSYOBONRV-IUYQGCFVBQ
Jmol-3D images	Image
PubChem	71957
SMILES C[C@@H](C(=O)N[C@@H](C)P(=O)(O)O)N
Properties
Chemical formula	C₅H₁₃N₂O₄P
Molar mass	196.14 g/mol
Melting point	295–297 °C (563–567 °F; 568–570 K) (decomp)
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Alafosfalin is an phosphonodipeptide with antibacterial^[1] and antifungal^[2] properties.

References

↑ Atherton, Frank R.; Hassall, Cedric H.; Lambert, Robert W. (January 1986). "Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid". Journal of Medicinal Chemistry 29 (1): 29–40. doi:10.1021/jm00151a005.
↑ Khomutov, Radii M.; Osipova, Tatyana I.; Khurs, Elena N.; Dzhavakhiya, Vitalii G. (November 2008). "Synthesis of alafosfalin and its phosphinic analogue and their fungicidal activity". Mendeleev Communications 18 (6): 295–296. doi:10.1016/j.mencom.2008.11.001.