Afovirsen
| Names | |
|---|---|
| Other names
ISIS 8741 | |
| Identifiers | |
| 151356-08-0 | |
| PubChem | 71587499 |
| Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
| Infobox references | |
Afovirsen is an oligonucleotide capable of antisense interactions with mRNA of human papillomavirus. It has been investigated as a tool for diagnostics and therapeutics.[1][2]
Nucleic Acid Sequence
Afovirsen consists of a sequence of 20 nucleic acids
ttgcttccat cttcctcgtc
References
- ↑ Crooke, RM; Graham, MJ; Cooke, ME; Crooke, ST (October 1995). "In vitro pharmacokinetics of phosphorothioate antisense oligonucleotides.". The Journal of pharmacology and experimental therapeutics 275 (1): 462–73. PMID 7562586.
- ↑ Liang, H; Nishioka, Y; Reich, C F; Pisetsky, D S; Lipsky, P E (1 September 1996). "Activation of human B cells by phosphorothioate oligodeoxynucleotides.". Journal of Clinical Investigation 98 (5): 1119–1129. doi:10.1172/JCI118894.