Aceglatone

Aceglatone
Systematic (IUPAC) name

(3R,3aR,6S,6aR)-2,5-Dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate
Clinical data
Trade names	Glucaron
AHFS/Drugs.com	International Drug Names
Identifiers
CAS Registry Number	642-83-1^N
ATC code	None
PubChem	CID 636372
ChemSpider	599998^Y
UNII	347Q3OOJ13^Y
ChEMBL	CHEMBL2103781^N
Synonyms	D-Glucaric acid di-γ-lactone 2,5-diacetate 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
Chemical data
Formula	C₁₀H₁₀O₈
Molecular mass	258.18 g/mol
SMILES O=C1O[C@H]2[C@@H](OC(=O)C)C(=O)O[C@H]2[C@@H]1OC(=O)C
InChI InChI=1S/C10H10O8/c1-3(11)15-7-5-6(18-9(7)13)8(10(14)17-5)16-4(2)12/h5-8H,1-2H3/t5-,6-,7-,8+/m1/s1 ^Y Key:ZOZKYEHVNDEUCO-XUTVFYLZSA-N ^Y
Physical data
Melting point	185 to 186 °C (365 to 367 °F) ^[1]
N (what is this?) (verify)

Aceglatone (Glucaron) is an antineoplastic drug available in Japan.^[2]

It is an inhibitor of the enzyme β-glucuronidase.^[3]

References

↑ Merck Index, 11th Edition, 20
↑ Glucaron, drugs.com
↑ Iida, Ryohei; Nagata, Sachiko; Kakimoto, Morio; Akaike, Hiroaki; Watanabe, Hiroko; Shioya, Akitoshi (1965). "2,5-Di-O-acetyl-D-glucosaccharo-(1→4)(6→3)-dilactone, a new potent β-glucuronidase inhibitor". Japanese Journal of Pharmacology 15 (1): 88–90. doi:10.1254/jjp.15.88.