Aceglatone
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Systematic (IUPAC) name | |
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(3R,3aR,6S,6aR)-2,5-Dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate | |
Clinical data | |
Trade names | Glucaron |
AHFS/Drugs.com | International Drug Names |
Identifiers | |
642-83-1 ![]() | |
None | |
PubChem | CID 636372 |
ChemSpider |
599998 ![]() |
UNII |
347Q3OOJ13 ![]() |
ChEMBL |
CHEMBL2103781 ![]() |
Synonyms |
D-Glucaric acid di-γ-lactone 2,5-diacetate 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone |
Chemical data | |
Formula | C10H10O8 |
258.18 g/mol | |
SMILES
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Physical data | |
Melting point | 185 to 186 °C (365 to 367 °F) [1] |
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Aceglatone (Glucaron) is an antineoplastic drug available in Japan.[2]
It is an inhibitor of the enzyme β-glucuronidase.[3]
References
- ↑ Merck Index, 11th Edition, 20
- ↑ Glucaron, drugs.com
- ↑ Iida, Ryohei; Nagata, Sachiko; Kakimoto, Morio; Akaike, Hiroaki; Watanabe, Hiroko; Shioya, Akitoshi (1965). "2,5-Di-O-acetyl-D-glucosaccharo-(1→4)(6→3)-dilactone, a new potent β-glucuronidase inhibitor". Japanese Journal of Pharmacology 15 (1): 88–90. doi:10.1254/jjp.15.88.