ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma | |||||||||||||
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Identifiers | |||||||||||||
Symbols | ARHGDIG ; RHOGDI-3 | ||||||||||||
External IDs | OMIM: 602844 MGI: 108430 HomoloGene: 7337 GeneCards: ARHGDIG Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 398 | 14570 | |||||||||||
Ensembl | ENSG00000242173 | ENSMUSG00000073433 | |||||||||||
UniProt | Q99819 | Q62160 | |||||||||||
RefSeq (mRNA) | NM_001176 | NM_008113 | |||||||||||
RefSeq (protein) | NP_001167 | NP_032139 | |||||||||||
Location (UCSC) | Chr 16: 0.32 – 0.33 Mb | Chr 17: 26.2 – 26.21 Mb | |||||||||||
PubMed search | |||||||||||||
Rho GDP-dissociation inhibitor 3 is a protein that in humans is encoded by the ARHGDIG gene.[1][2][3]
Interactions
ARHGDIG has been shown to interact with RHOB.[4]
References
- ↑ Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L et al. (May 1997). "RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas". Proc Natl Acad Sci U S A 94 (9): 4279–84. doi:10.1073/pnas.94.9.4279. PMC 20713. PMID 9113980.
- ↑ Brunet N, Morin A, Olofsson B (Apr 2002). "RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain". Traffic 3 (5): 342–57. doi:10.1034/j.1600-0854.2002.30504.x. PMID 11967128.
- ↑ "Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma".
- ↑ Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A et al. (Nov 1996). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998. Vancouver style error (help)
Further reading
- Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A et al. (1997). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998. Vancouver style error (help)
- Adra CN, Iyengar AR, Syed FA, Kanaan IN, Rilo HL, Yu W et al. (1998). "Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3". Genomics 53 (1): 104–9. doi:10.1006/geno.1998.5482. PMID 9787082.
- Elenich LA, Nandi D, Kent AE, McCluskey TS, Cruz M, Iyer MN et al. (1999). "The complete primary structure of mouse 20S proteasomes". Immunogenetics 49 (10): 835–42. doi:10.1007/s002510050562. PMID 10436176.
- Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
- Li X, Bu X, Lu B, Avraham H, Flavell RA, Lim B (2002). "The Hematopoiesis-Specific GTP-Binding Protein RhoH Is GTPase Deficient and Modulates Activities of Other Rho GTPases by an Inhibitory Function". Mol. Cell. Biol. 22 (4): 1158–71. doi:10.1128/MCB.22.4.1158-1171.2002. PMC 134637. PMID 11809807.
- del Pozo MA, Alderson NB, Kiosses WB, Chiang HH, Anderson RG, Schwartz MA (2004). "Integrins regulate Rac targeting by internalization of membrane domains". Science 303 (5659): 839–42. doi:10.1126/science.1092571. PMID 14764880.
- Dransart E, Morin A, Cherfils J, Olofsson B (2005). "Uncoupling of inhibitory and shuttling functions of rho GDP dissociation inhibitors". J. Biol. Chem. 280 (6): 4674–83. doi:10.1074/jbc.M409741200. PMID 15513926.