APOL6

Apolipoprotein L, 6

Identifiers

APOL6 ; APOL-VI; APOLVI

External IDs

OMIM: 607256 MGI: 1919189 HomoloGene: 49940 GeneCards: APOL6 Gene

Gene ontology
Molecular function	• lipid binding
Cellular component	• extracellular region • cytoplasm
Biological process	• lipid transport • lipoprotein metabolic process
Sources: Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

ENSG00000221963

ENSMUSG00000033576

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

Chr 22:
36.04 – 36.06 Mb

Chr 15:
77.04 – 77.06 Mb

PubMed search

Apolipoprotein L6 is a protein that in humans is encoded by the APOL6 gene.^[1]^[2]^[3]

This gene is a member of the apolipoprotein L gene family. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids or allow the binding of lipids to organelles.^[3]

References

↑ Page NM, Butlin DJ, Lomthaisong K, Lowry PJ (May 2001). "The human apolipoprotein L gene cluster: identification, classification, and sites of distribution". Genomics 74 (1): 71–8. doi:10.1006/geno.2001.6534. PMID 11374903.
↑ Liu Z, Lu H, Jiang Z, Pastuszyn A, Hu CA (Jan 2005). "Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells". Mol Cancer Res 3 (1): 21–31. PMID 15671246.
↑ 3.0 3.1 "Entrez Gene: APOL6 apolipoprotein L, 6".

Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Dominguez O, Ashhab Y, Sabater L et al. (1999). "Cloning of ARE-containing genes by AU-motif-directed display.". Genomics 54 (2): 278–86. doi:10.1006/geno.1998.5548. PMID 9828130.
Dunham I, Shimizu N, Roe BA et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Collins JE, Wright CL, Edwards CA et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.