ANKRD2
| Ankyrin repeat domain 2 (stretch responsive muscle) | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ANKRD2 ; ARPP | ||||||||||||
| External IDs | OMIM: 610734 MGI: 1861447 HomoloGene: 10568 GeneCards: ANKRD2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 26287 | 56642 | |||||||||||
| Ensembl | ENSG00000165887 | ENSMUSG00000025172 | |||||||||||
| UniProt | Q9GZV1 | Q9WV06 | |||||||||||
| RefSeq (mRNA) | NM_001129981 | NM_020033 | |||||||||||
| RefSeq (protein) | NP_001123453 | NP_064417 | |||||||||||
| Location (UCSC) | Chr 10: 99.33 – 99.34 Mb | Chr 19: 42.04 – 42.05 Mb | |||||||||||
| PubMed search | |||||||||||||
Ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the ANKRD2 gene.[1][2][3][4]
Interactions
ANKRD2 has been shown to interact with Y box binding protein 1,[2] Telethonin,[2] Promyelocytic leukemia protein[2] and P53.[2]
References
- ↑ Kemp TJ, Sadusky TJ, Saltisi F, Carey N, Moss J, Yang SY et al. (Sep 2000). "Identification of Ankrd2, a novel skeletal muscle gene coding for a stretch-responsive ankyrin-repeat protein". Genomics 66 (3): 229–41. doi:10.1006/geno.2000.6213. PMID 10873377.
- ↑ 2.0 2.1 2.2 2.3 2.4 Kojic S, Medeot E, Guccione E, Krmac H, Zara I, Martinelli V et al. (May 2004). "The Ankrd2 protein, a link between the sarcomere and the nucleus in skeletal muscle". J. Mol. Biol. 339 (2): 313–25. doi:10.1016/j.jmb.2004.03.071. PMID 15136035.
- ↑ Mckoy G, Hou Y, Yang SY, Vega Avelaira D, Degens H, Goldspink G et al. (May 2005). "Expression of Ankrd2 in fast and slow muscles and its response to stretch are consistent with a role in slow muscle function". J. Appl. Physiol. 98 (6): 2337–43; discussion 2320. doi:10.1152/japplphysiol.01046.2004. PMID 15677738.
- ↑ "Entrez Gene: ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)".
Further reading
- Sosovec V, Ivicic L, Gaspar I, L'Achová B (1975). "[Incidence of benign conjugated hyperbilirubinemia with pigment in the liver in Spis (Dubin-Johnson syndrome) II. Attempts at screening of carrier state by means of BSP test]". Cesk Gastroenterol Vyz 29 (8): 517–26. PMID 1204005. Vancouver style error (help)
- Pallavicini A, Kojić S, Bean C, Vainzof M, Salamon M, Ievolella C et al. (2001). "Characterization of human skeletal muscle Ankrd2". Biochem. Biophys. Res. Commun. 285 (2): 378–86. doi:10.1006/bbrc.2001.5131. PMID 11444853. Vancouver style error (help)
- Moriyama M, Tsukamoto Y, Fujiwara M, Kondo G, Nakada C, Baba T et al. (2001). "Identification of a novel human ankyrin-repeated protein homologous to CARP". Biochem. Biophys. Res. Commun. 285 (3): 715–23. doi:10.1006/bbrc.2001.5216. PMID 11453652.
- Laveder P, De Pittà C, Toppo S, Valle G, Lanfranchi G (2002). "A two-step strategy for constructing specifically self-subtracted cDNA libraries". Nucleic Acids Res. 30 (9): e38. doi:10.1093/nar/30.9.e38. PMC 113861. PMID 11972353. Vancouver style error (help)
- Tsukamoto Y, Senda T, Nakano T, Nakada C, Hida T, Ishiguro N et al. (2002). "Arpp, a new homolog of carp, is preferentially expressed in type 1 skeletal muscle fibers and is markedly induced by denervation". Lab. Invest. 82 (5): 645–55. doi:10.1038/labinvest.3780459. PMID 12004005.
- Nakamura K, Nakada C, Takeuchi K, Osaki M, Shomori K, Kato S et al. (2003). "Altered expression of cardiac ankyrin repeat protein and its homologue, ankyrin repeat protein with PEST and proline-rich region, in atrophic muscles in amyotrophic lateral sclerosis". Pathobiology 70 (4): 197–203. doi:10.1159/000069329. PMID 12679596.
- Miller MK, Bang ML, Witt CC, Labeit D, Trombitas C, Watanabe K et al. (2003). "The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules". J. Mol. Biol. 333 (5): 951–64. doi:10.1016/j.jmb.2003.09.012. PMID 14583192.
- Ishiguro N, Motoi T, Osaki M, Araki N, Minamizaki T, Moriyama M et al. (2005). "Immunohistochemical analysis of a muscle ankyrin-repeat protein, Arpp, in paraffin-embedded tumors: evaluation of Arpp as a tumor marker for rhabdomyosarcoma". Hum. Pathol. 36 (6): 620–5. doi:10.1016/j.humpath.2005.04.014. PMID 16021567.
- Shomori K, Nagashima Y, Kuroda N, Honjo A, Tsukamoto Y, Tokuyasu N et al. (2007). "ARPP protein is selectively expressed in renal oncocytoma, but rarely in renal cell carcinomas". Mod. Pathol. 20 (2): 199–207. doi:10.1038/modpathol.3800730. PMID 17206105.