ANAPC11

Anaphase promoting complex subunit 11
Identifiers
SymbolsANAPC11 ; APC11; Apc11p
External IDsOMIM: 614534 MGI: 1913406 HomoloGene: 41136 GeneCards: ANAPC11 Gene
Orthologs
SpeciesHumanMouse
Entrez5152966156
EnsemblENSG00000141552ENSMUSG00000025135
UniProtQ9NYG5Q9CPX9
RefSeq (mRNA)NM_001002244NM_001038230
RefSeq (protein)NP_001002244NP_001033319
Location (UCSC)Chr 17:
79.85 – 79.86 Mb
Chr 11:
120.6 – 120.61 Mb
PubMed search

Anaphase-promoting complex subunit 11 is an enzyme that in humans is encoded by the ANAPC11 gene.[1][2]

Interactions

ANAPC11 has been shown to interact with ANAPC2[3][4] and CDC27.[1][5]

References

  1. 1.0 1.1 Gmachl M, Gieffers C, Podtelejnikov AV, Mann M, Peters JM (Sep 2000). "The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex". Proc Natl Acad Sci U S A 97 (16): 8973–8. doi:10.1073/pnas.97.16.8973. PMC 16806. PMID 10922056.
  2. "Entrez Gene: ANAPC11 APC11 anaphase promoting complex subunit 11 homolog (yeast)".
  3. Tang, Z; Li B; Bharadwaj R; Zhu H; Ozkan E; Hakala K; Deisenhofer J; Yu H (Dec 2001). "APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex". Mol. Biol. Cell (United States) 12 (12): 3839–51. doi:10.1091/mbc.12.12.3839. ISSN 1059-1524. PMC 60759. PMID 11739784.
  4. Ohta, T; Michel J J; Schottelius A J; Xiong Y (Apr 1999). "ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity". Mol. Cell (UNITED STATES) 3 (4): 535–41. doi:10.1016/S1097-2765(00)80482-7. ISSN 1097-2765. PMID 10230407.
  5. Vodermaier, Hartmut C; Gieffers, Christian; Maurer-Stroh, Sebastian; Eisenhaber, Frank; Peters, Jan-Michael (Sep 2003). "TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1". Curr. Biol. (England) 13 (17): 1459–68. doi:10.1016/S0960-9822(03)00581-5. ISSN 0960-9822. PMID 12956947.

Further reading