ABCF2
| ATP-binding cassette, sub-family F (GCN20), member 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ABCF2 ; ABC28; EST133090; HUSSY18 | ||||||||||||
| External IDs | OMIM: 612510 MGI: 1351657 HomoloGene: 21408 GeneCards: ABCF2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10061 | 27407 | |||||||||||
| Ensembl | ENSG00000033050 | ENSMUSG00000028953 | |||||||||||
| UniProt | Q9UG63 | Q99LE6 | |||||||||||
| RefSeq (mRNA) | NM_005692 | NM_001190443 | |||||||||||
| RefSeq (protein) | NP_005683 | NP_001177372 | |||||||||||
| Location (UCSC) | Chr 7: 150.9 – 150.92 Mb | Chr 5: 24.57 – 24.58 Mb | |||||||||||
| PubMed search | |||||||||||||
ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.[1][2]
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.[2]
See also
References
- ↑ Allikmets R, Gerrard B, Hutchinson A, Dean M (Feb 1997). "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database". Hum Mol Genet 5 (10): 1649–55. doi:10.1093/hmg/5.10.1649. PMID 8894702.
- ↑ 2.0 2.1 "Entrez Gene: ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2".
Further reading
- Klein I, Sarkadi B, Váradi A (2000). "An inventory of the human ABC proteins.". Biochim. Biophys. Acta 1461 (2): 237–62. doi:10.1016/s0005-2736(99)00161-3. PMID 10581359.
- Dean M, Rzhetsky A, Allikmets R (2001). "The human ATP-binding cassette (ABC) transporter superfamily.". Genome Res. 11 (7): 1156–66. doi:10.1101/gr.184901. PMID 11435397.
- Hogue DL, Liu L, Ling V (1999). "Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein.". J. Mol. Biol. 285 (1): 379–89. doi:10.1006/jmbi.1998.2259. PMID 9878413.
- Zhang F, Hogue DL, Liu L et al. (2000). "M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein.". FEBS Lett. 478 (1–2): 89–94. doi:10.1016/S0014-5793(00)01823-8. PMID 10922475.
- Ye Z, Connor JR (2000). "cDNA cloning by amplification of circularized first strand cDNAs reveals non-IRE-regulated iron-responsive mRNAs". Biochem. Biophys. Res. Commun. 275 (1): 223–7. doi:10.1006/bbrc.2000.3282. PMID 10944468.
- Stanchi F, Bertocco E, Toppo S et al. (2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast 18 (1): 69–80. doi:10.1002/1097-0061(200101)18:1<69::AID-YEA647>3.0.CO;2-H. PMID 11124703.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Scherer SW, Cheung J, MacDonald JR et al. (2003). "Human chromosome 7: DNA sequence and biology". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
- Hillier LW, Fulton RS, Fulton LA et al. (2003). "The DNA sequence of human chromosome 7". Nature 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
- Gerhard DS, Wagner L, Feingold EA et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Tsuda H, Ito YM, Ohashi Y et al. (2006). "Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses". Clin. Cancer Res. 11 (19 Pt 1): 6880–8. doi:10.1158/1078-0432.CCR-05-0751. PMID 16203778.
- Nishimura S, Tsuda H, Ito K et al. (2007). "Differential expression of ABCF2 protein among different histologic types of epithelial ovarian cancer and in clear cell adenocarcinomas of different organs". Hum. Pathol. 38 (1): 134–9. doi:10.1016/j.humpath.2006.06.026. PMID 16996567.
External links
- ABCF2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- ABCF2 human gene location in the UCSC Genome Browser.
- ABCF2 human gene details in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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