4-hydroxybenzoate nonaprenyltransferase
| 4-hydroxybenzoate nonaprenyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.39 | ||||||||
| CAS number | 9030-77-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
| |||||||||
In enzymology, a 4-hydroxybenzoate nonaprenyltransferase (EC 2.5.1.39) is an enzyme that catalyzes the chemical reaction
- solanesyl diphosphate (nonaisoprenol diphosphate) + 4-hydroxybenzoate
diphosphate + nonaprenyl-4-hydroxybenzoate
Thus, the two substrates of this enzyme are nonaisoprenol diphosphate and 4-hydroxybenzoate, whereas its two products are diphosphate and nonaprenyl-4-hydroxybenzoate.
This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. This enzyme participates in ubiquinone biosynthesis.
Nomenclature
The systematic name of this enzyme class is solanesyl-diphosphate:4-hydroxybenzoate nonaprenyltransferase. Other names in common use include:
- nonaprenyl-4-hydroxybenzoate transferase,
- 4-hydroxybenzoate transferase,
- p-hydroxybenzoate dimethylallyltransferase,
- p-hydroxybenzoate polyprenyltransferase,
- p-hydroxybenzoic acid-polyprenyl transferase, and
- p-hydroxybenzoic-polyprenyl transferase.
(See also, the page on 4-hydroxybenzoate polyprenyltransferase).
References
- Kalen A, Appelkvist EL, Chojnacki T, Dallner G (1990). "Nonaprenyl-4-hydroxybenzoate transferase, an enzyme involved in ubiquinone biosynthesis, in the endoplasmic reticulum-Golgi system of rat liver". J. Biol. Chem. 265 (2): 1158–64. PMID 2295606.