4-Aminoquinoline

4-Aminoquinoline
Structural formula of 4-aminoquinoline
Space-filling model of the 4-aminoquinoline molecule
Names
IUPAC name
quinolin-4-amine
Identifiers
578-68-7 
ChEMBL ChEMBL58146 Yes
ChemSpider 61751 Yes
Jmol-3D images Image
PubChem 68476
UNII GTE5P5L97N Yes
Properties
Molecular formula
C9H8N2
Molar mass 144.17 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.

A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections. Examples include amodiaquine, chloroquine, and hydroxychloroquine.[1]

References

  1. Bray PG, Hawley SR, Ward SA (1996). "4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake". Mol. Pharmacol. 50 (6): 1551–8. PMID 8967977.

External links