4,5-Dihydroorotic acid

4,5-Dihydroorotic acid
Names

IUPAC name 2,6-dioxo-1,3-diazinane-4-carboxylic acid
Identifiers
CAS Registry Number	155-54-4^N
ChEBI	CHEBI:30865^Y
ChEMBL	ChEMBL75782^Y
ChemSpider	628^Y
InChI InChI=1S/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)^Y Key: UFIVEPVSAGBUSI-UHFFFAOYSA-N^Y InChI=1/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11) Key: UFIVEPVSAGBUSI-UHFFFAOYAI
Jmol-3D images	Image
MeSH	4,5-dihydroorotic+acid
PubChem	648
SMILES O=C1NC(=O)NC(C(=O)O)C1
Properties
Chemical formula	C₅H₆N₂O₄
Molar mass	158.112 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
N verify (what is: Y/N?)
Infobox references

4,5-Dihydroorotic acid is a derivative of orotic acid which serves as an intermediate in pyrimidine biosynthesis.^[1]

References

↑ Francois Lacroute (March 1968). "Regulation of Pyrimidine Biosynthesis in Saccharomyces cerevisiae1". J. Bacteriol. 95: 824–832.

Nucleotide metabolic intermediates

Purine metabolism

Anabolism

R5P→IMP:	R5P PRPP PRA GAR FGAR FGAM AIR CAIR SAICAR AICAR FAICAR

IMP→AMP:	Adenylosuccinate

IMP→GMP:	Xanthosine monophosphate

Catabolism

Pyrimidine metabolism

Anabolism

Catabolism

uracil:	Dihydrouracil 3-Ureidopropionic acid β-Alanine

thymine:	Dihydrothymine β-Ureidoisobutyric acid 3-Aminoisobutyric acid

Index of inborn errors of metabolism

Description	Metabolism Enzymes and pathways: citric acid cycle enzymes pentose phosphate intermediates glycoproteins enzymes glycosaminoglycans proteoglycan enzymes phospholipid metabolism cholesterol and steroid intermediates sphingolipids enzymes eicosanoids enzymes amino acid intermediates urea cycle enzymes nucleotide intermediates

Disorders	Citric acid cycle and electron transport chain Glycoprotein Proteoglycan Fatty-acid Phospholipid Cholesterol and steroid Eicosanoid Amino acid Purine-pyrimidine Heme metabolism Symptoms and signs

Treatment	Drugs other

Index of biochemical families

Carbohydrates	Alcohols Glycoproteins Glycosides

Lipids	Eicosanoids Fatty acids intermediates Glycerides Phospholipids Sphingolipids Steroids

Nucleic acids	Constituents intermediates

Proteins	Amino acids intermediates

Other	Tetrapyrroles intermediates