3-hydroxybenzoate—CoA ligase

3-hydroxybenzoate—CoA ligase
Identifiers
EC number 6.2.1.37
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

3-hydroxybenzoate—CoA ligase (EC 6.2.1.37, 3-hydroxybenzoyl-CoA synthetase, 3-hydroxybenzoate-coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase) is an enzyme with system name 3-hydroxybenzoate:CoA ligase (AMP-forming).[1] This enzyme catalyses the following chemical reaction

ATP + 3-hydroxybenzoate + CoA \rightleftharpoons AMP + diphosphate + 3-hydroxybenzoyl-CoA

The enzyme works equally well with 4-hydroxybenzoate.

References

  1. Laempe, D., Jahn, M., Breese, K., Schägger, H. and Fuchs, G. (2001). "Anaerobic metabolism of 3-hydroxybenzoate by the denitrifying bacterium Thauera aromatica". J. Bacteriol. 183: 968–979. doi:10.1128/jb.183.3.968-979.2001. PMID 11208796.

External links