3-Methoxy-4-hydroxyphenylglycol
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| Names | |
|---|---|
| IUPAC name
1-(4-Hydroxy-3-methoxyphenyl) ethane-1,2-diol | |
| Other names
MHPG | |
| Identifiers | |
67423-45-4  | |
| ChemSpider | 10348  |
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| Jmol-3D images | Image Image |
| KEGG | C05594 |
| MeSH | Methoxyhydroxyphenylglycol |
| PubChem | 10805 |
| |
| Properties | |
| C9H12O4 | |
| Molar mass | 184.18918 |
| Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | |
| verify (what is: /?) | |
| Infobox references | |
3-Methoxy-4-hydroxyphenylglycol (MHPG, MOPEG) is a metabolite of norepinephrine degradation. In the brain, it is the principal norepinephrine metabolite. It is released into the blood and cerebrospinal fluid,[1] and a blood sample of it may therefore be an indication of recent sympathetic nervous system activity.
Low levels of it in the blood and CSF are connected to Anorexia nervosa.
Norepinephrine degradation. 3-Methoxy-4-hydroxyphenylglycol is shown at right. Enzymes are shown in boxes.[2]
References
- ↑ Increase in cerebrospinal fluid and plasma levels of 3-methoxy-4- hydroxyphenylglycol in acute stroke T Kanda, K Azuma, F Sakai and Y Tazaki. Department of Internal Medicine, School of Medicine, Kitasato University, Sagamihara, Japan.
- ↑ Figure 11-4 in: Rod Flower; Humphrey P. Rang; Maureen M. Dale; Ritter, James M. (2007). Rang & Dale's pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-06911-5.
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