1,1,2,2-Tetrachloroethane

1,1,2,2-Tetrachloroethane^[1]

Names
IUPAC name 1,1,2,2-Tetrachloroethane
Other names s-Tetrachloroethane Acetylene tetrachloride R-130 TeCA
Identifiers
CAS Registry Number	79-34-5 Y
ChEBI	CHEBI:36026 Y
ChEMBL	ChEMBL47258 Y
ChemSpider	6342 Y
InChI InChI=1S/C2H2Cl4/c3-1(4)2(5)6/h1-2H Y Key: QPFMBZIOSGYJDE-UHFFFAOYSA-N Y InChI=1/C2H2Cl4/c3-1(4)2(5)6/h1-2H Key: QPFMBZIOSGYJDE-UHFFFAOYAH
Jmol-3D images	Image
KEGG	C19534 N
PubChem	6591
SMILES ClC(Cl)C(Cl)Cl
Properties
Molecular formula	C2H2Cl4
Molar mass	167.85 g·mol−1
Appearance	Clear liquid
Density	1.59 g/cm3
Melting point	−44 °C (−47 °F; 229 K)
Boiling point	146.5 °C (295.7 °F; 419.6 K)
Solubility in water	1 g/350 mL
Hazards
US health exposure limits (NIOSH):
PEL (Permissible)	TWA 5 ppm (35 mg/m3) [skin][2]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

1,1,2,2-Tetrachloroethane is a chlorinated derivative of ethane. It has the highest solvent power of any chlorinated hydrocarbon.^[1] As a refrigerant, it is used under the name R-130.

It was once widely used as a solvent and as an intermediate in the industrial production of trichloroethylene, tetrachloroethylene, and 1,2-dichloroethylene.^[3] However, 1,1,2,2-tetrachloroethane is no longer used much in the United States due to concerns about its toxicity.^[4]

Chronic inhalation exposure in humans results in jaundice and an enlarged liver, headaches, tremors, dizziness, numbness, and drowsiness. The U.S. Environmental Protection Agency has classified it as a Group C possible human carcinogen.^[4]

For occupational exposure limits, the Occupational Safety and Health Administration has set a permissible exposure limit for dermal exposures at 5 ppm over an eight-hour time-weighted average. The National Institute for Occupational Safety and Health has a more protective recommended exposure limit for dermal exposures at 1 ppm over an eight-hour time-weighted average.^[5]

See also

• 1,1,1,2-Tetrachloroethane

References

1. ↑ 1.0 1.1 Merck Index, 11th Edition, 9125.
2. ↑ "NIOSH Pocket Guide to Chemical Hazards #0598". National Institute for Occupational Safety and Health (NIOSH). 
3. ↑ Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological Profile for 1,1,2,2-Tetrachloroethane (Update). U.S. Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. 1996.
4. ↑ 4.0 4.1 Tetrachloroethane at U.S. EPA
5. ↑ CDC - NIOSH Pocket Guide to Chemical Hazards