Pausinystalia yohimbe

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Yohimbe
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Asterids
Order: Gentianales
Family: Rubiaceae
Genus: Pausinystalia
Species: P. yohimbe
Binomial name
Pausinystalia yohimbe

Pausinystalia yohimbe (Yohimbe), formerly known as Corynanthe yohimbe and sometimes spelled johimbe,[1][2] is a psychoactive plant that contains the MAOI alkaloid yohimbine. It is widely distributed over-the-counter as an herbal aphrodisiac.

Originating from the bark of an Africa tree, it has been purported to be helpful for men with erectile dysfunction (ED). This herbal medication can cause tachycardia[citation needed] and hypertension[citation needed] if improperly dosed and should generally only be used under the supervision of a practitioner knowledgeable in herbal medicine.

In addition to yohimbine, Yohimbe also contains 55 other alkaloids. Yohimbine accounts for 1-20% of its total alkaloid content. Among the others is corynanthine, an alpha-1 adrenergic receptor blocker.[3] Hence, the use of yohimbe extract in sufficient dosages may provide concomitant alpha-1 and alpha-2 adrenoceptors blockade and thus may better enhance erections than yohimbine alone.[4]

See also

References

  1. McGuffin, Michael; Hobbs, Christopher; Upton, Roy et al., eds. (1997). American Herbal Products Association's Botanical Safety Handbook. CRC Press. p. 83. ISBN 9780849316753. 
  2. Wildman, Robert E.C.; Medeiros, Denis M. (2000). Advanced Human Nutrition. CRC Series in Modern Nutrition 22. CRC Press. p. 390. ISBN 9780849385667. 
  3. Doxey, JC; Lane AC, Roach AG, Virdee NK (Feb 1984). "Comparison of the alpha-adrenoceptor antagonist profiles of idazoxan (RX 781094), yohimbine, rauwolscine and corynanthine.". Naunyn-Schmied Arch Pharmacol 325 (2): 136–144. PMID 6144048. 
  4. Saenz De Tejada, I; Kim, NN; Goldstein, I; Traish, AM (2000). "Regulation of pre-synaptic alpha adrenergic activity in the corpus cavernosum". International journal of impotence research 12 Suppl 1: S20–25. PMID 10845761.


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