Voclosporin
Voclosporin | ||
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IUPAC name (3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4,6-heptadien-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone | ||
Other names VCS, ISA247, Luveniq | ||
Identifiers | ||
PubChem | 6918486 | |
ChemSpider | 5293683 | |
Jmol-3D images | {{#if:O=C1N(C)[C@H](C(=O)N[C@H](C(=O)N(C)CC(=O)N(C)[C@H](C(=O)N[C@H](C(=O)N(C)[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N(C)[C@H](C(=O)N(C)[C@H]1C(C)C)CC(C)C)CC(C)C)C)C)C)CC(C)C)C(C)C)CC(C)C)CC)[C@H](O)[C@H](C)C\C=C\C=C|Image 1 | |
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Properties | ||
Molecular formula | C63H111N11O12 | |
Molar mass | 1,214.62 g mol−1 | |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
Infobox references | ||
Voclosporin is an experimental immunosuppressant drug being developed by Isotechnika and Lux Biosciences.[1] It is being studied for use in solid organ transplantation and autoimmune diseases such as psoriasis. It is an analog of ciclosporin that has enhanced action against calcineurin and greater metabolic stability.[2]
References
- ↑ "Voclosporin". Psoriasis Cure Now. Retrieved October 19, 2012.
- ↑ "What is voclosporin?". Isotechnika. Retrieved October 19, 2012.