Vesicle associated membrane proteins (VAMP) are a family of SNARE proteins with similar structure, and are mostly involved in vesicle fusion.
- VAMP3 (known as cellubrevin) is ubiquitously expressed and participates in regulated and constitutive exocytosis as a constituent of secretory granules and secretory vesicles.
- VAMP5 and VAMP7 (SYBL1) participate in constitutive exocytosis.
- VAMP5 is a constituent of secretory vesicles, myotubes and tubulovesicular structures.
- VAMP7 is found both in secretory granules and endosomes.
- VAMP8 (known as endobrevin) participates in endocytosis and is found in early endosomes. VAMP8 also participates the regulated exocytosis in pancreatic acinar cells.
- VAMP4 is involved in transport from the Golgi.[1]
References
- ↑ Steegmaier M, Klumperman J, Foletti DL, Yoo JS, Scheller RH (1999). "Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking". Mol. Biol. Cell 10 (6): 1957–72. PMC 25394. PMID 10359608.
External links
|
---|
| Synaptic vesicle |
|
---|
| COPI | |
---|
| COPII | |
---|
| RME/Clathrin | |
---|
| Caveolae | |
---|
| Other/ungrouped |
Vesicle formation |
Adaptor protein complex 1: | |
---|
| Adaptor protein complex 2: | |
---|
| Adaptor protein complex 3: | |
---|
| Adaptor protein complex 4: | |
---|
| | | | | | | BLOC-2: | |
---|
| BLOC-3: | |
---|
| Coats: | |
---|
|
---|
| Small GTPase | |
---|
| Other | |
---|
|
---|
|
see also vesicular transport protein disorders B memb: cead, trns (1A, 1C, 1F, 2A, 3A1, 3A2-3, 3D), other |
|