UBE2E2
From Wikipedia, the free encyclopedia
| Ubiquitin-conjugating enzyme E2E 2 | |||||||||||||
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 PDB rendering based on 1y6l. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | UBE2E2; UBCH8 | ||||||||||||
| External IDs | OMIM: 602163 MGI: 2384997 HomoloGene: 77337 GeneCards: UBE2E2 Gene | ||||||||||||
| EC number | 6.3.2.19 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 7325 | 218793 | |||||||||||
| Ensembl | ENSG00000182247 | ENSMUSG00000058317 | |||||||||||
| UniProt | Q96LR5 | Q91W82 | |||||||||||
| RefSeq (mRNA) | NM_152653 | NM_144839 | |||||||||||
| RefSeq (protein) | NP_689866 | NP_659088 | |||||||||||
| Location (UCSC) | Chr 3: 23.24 – 23.63 Mb | Chr 14: 18.57 – 18.89 Mb | |||||||||||
| PubMed search | |||||||||||||
Ubiquitin-conjugating enzyme E2 E2 is a protein that in humans is encoded by the UBE2E2 gene.[1][2]
References
- ↑ Kimura M, Hattori T, Matsuda Y, Yoshioka T, Sumi N, Umeda Y, Nakashima S, Okano Y (Dec 1997). "cDNA cloning, characterization, and chromosome mapping of UBE2E2 encoding a human ubiquitin-conjugating E2 enzyme". Cytogenet Cell Genet 78 (2): 107–11. doi:10.1159/000134639. PMID 9371400.
- ↑ "Entrez Gene: UBE2E2 ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)".
Further reading
- Auffray C, Behar G, Bois F et al. (1995). "[IMAGE: molecular integration of the analysis of the human genome and its expression]". C. R. Acad. Sci. III, Sci. Vie 318 (2): 263–72. PMID 7757816.
- Moynihan TP, Ardley HC, Nuber U et al. (1999). "The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1". J. Biol. Chem. 274 (43): 30963–8. doi:10.1074/jbc.274.43.30963. PMID 10521492.
- Niwa J, Ishigaki S, Doyu M et al. (2001). "A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity". Biochem. Biophys. Res. Commun. 281 (3): 706–13. doi:10.1006/bbrc.2001.4414. PMID 11237715.
- Pringa E, Martinez-Noel G, Muller U, Harbers K (2001). "Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes". J. Biol. Chem. 276 (22): 19617–23. doi:10.1074/jbc.M100192200. PMID 11274149.
- Ito K, Adachi S, Iwakami R et al. (2001). "N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8". Eur. J. Biochem. 268 (9): 2725–32. doi:10.1046/j.1432-1327.2001.02169.x. PMID 11322894.
- Wheeler TC, Chin LS, Li Y et al. (2002). "Regulation of synaptophysin degradation by mammalian homologues of seven in absentia". J. Biol. Chem. 277 (12): 10273–82. doi:10.1074/jbc.M107857200. PMID 11786535.
- Strausberg RL, Feingold EA, Grouse LH et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Kim KI, Giannakopoulos NV, Virgin HW, Zhang DE (2004). "Interferon-Inducible Ubiquitin E2, Ubc8, Is a Conjugating Enzyme for Protein ISGylation". Mol. Cell. Biol. 24 (21): 9592–600. doi:10.1128/MCB.24.21.9592-9600.2004. PMC 522249. PMID 15485925.
- Plafker SM, Plafker KS, Weissman AM, Macara IG (2005). "Ubiquitin charging of human class III ubiquitin-conjugating enzymes triggers their nuclear import". J. Cell Biol. 167 (4): 649–59. doi:10.1083/jcb.200406001. PMC 2172591. PMID 15545318.
- Takeuchi T, Iwahara S, Saeki Y et al. (2005). "Link between the Ubiquitin Conjugation System and the ISG15 Conjugation System: ISG15 Conjugation to the UbcH6 Ubiquitin E2 Enzyme". J. Biochem. 138 (6): 711–9. doi:10.1093/jb/mvi172. PMID 16428300.
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