Tolimidone

From Wikipedia, the free encyclopedia

Tolimidone

Systematic (IUPAC) name
5-(3-methylphenoxy)pyrimidin-2(1H)-one
Clinical data
Legal status	?
Identifiers
CAS number	41964-07-2
ATC code	?
PubChem	CID 39065
ChemSpider	35751
UNII	MU3JD8E9IS^Y
KEGG	D06182
Chemical data
Formula	C₁₁H₁₀N₂O₂
Mol. mass	202.21 g/mol
SMILES O=C2/N=C\C(\Oc1cc(ccc1)C)=C/N2

Tolimidole is a compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.

Synthesis

References

Lipinski, C. A.; Stam, J. G.; Pereira, J. N.; Ackerman, N. R.; Hess, H. J. (1980). "Bronchodilator and antiulcer phenoxypyrimidinones". Journal of Medicinal Chemistry 23 (9): 1026–31. doi:10.1021/jm00183a012. PMID 7411545.

Drugs for acid related disorders: Drugs for peptic ulcer and GERD/GORD (A02B)

H₂ antagonists ("-tidine")

Prostaglandins (E)/analogues ("-prost-")

Proton-pump inhibitors ("-prazole")

Other

See also: Helicobacter pylori eradication protocols

M: DIG

anat (t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug (A2A/2B/3/4/5/6/7/14/16), blte

This article is issued from Wikipedia. The text is available under the Creative Commons Attribution/Share Alike; additional terms may apply for the media files.