Tinyatoxin
From Wikipedia, the free encyclopedia
| Tinyatoxin | ||
|---|---|---|
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| Identifiers | ||
| CAS number | 58821-95-7  | |
| PubChem | 442098 | |
| MeSH | tinyatoxin | |
| Properties | ||
| Molecular formula | C36H38O8 | |
| Molar mass | 598.68 g mol−1 | |
(verify) (what is: / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
| Infobox references | ||
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| Heat | Above Peak (SR: 5,300,000,000) |
|---|---|
Tinyatoxin (TTX or TTN) is a highly irritant analog of resiniferatoxin and capsaicin. It occurs naturally in Euphorbia poissonii.[1]
It is a neurotoxin and (like its analogs) acts via vanilloid receptors of sensory nerves.[2] Tinyatoxin has a potential for pharmaceutical uses similar to uses of capsaicin. Tinyatoxin is about one third as strong as resiniferatoxin.
References
- ↑ Euphorbia poissonii in BoDD – Botanical Dermatology Database
- ↑ Szallasi, A. and Blumberg, P.M. (1991). "Characterization of vanilloid receptors in the dorsal horn of pig spinal cord". Brain Res 547 (2): 335–338. doi:10.1016/0006-8993(91)90982-2. PMID 1884211.
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