Thunberginol A

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Thunberginol A
Chemical structure of thunberginol A
IUPAC name

3-(3,4-dihydroxyphenyl)-8-hydroxyisochromen-1-one

Identifiers
CAS number 147666-80-6 YesY
PubChem 5321948
Jmol-3D images Image 1
Properties
Molecular formula C15H10O5
Molar mass 270.23 g/mol
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Thunberginol A is an isocoumarin found in Hydrangea macrophylla[1] and in its processed leaves form (Hydrangeae dulcis folium).[2][3]

References

  1. ↑ Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1999). "Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and thunberginols a and F from Hydrangea macrophylla SERINGE var. Thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats". Biological & Pharmaceutical Bulletin 22 (8): 870–872. doi:10.1248/bpb.22.870. PMID 10480329. INIST:1959604. 
  2. ↑ Yamahara, J.; Matsuda, H.; Shimoda, H.; Wariishi, N.; Yagi, N.; Murakami, N.; Yoshikawa, M. (1995). "Effects of thunberginol a contained in Hydrangeae dulcis forium on types I-IV allergies". Nihon yakurigaku zasshi. Folia pharmacologica Japonica (in Japanese) 105 (5): 365–379. PMID 7628785. 
  3. ↑ Matsuda, H.; Shimoda, H.; Yamahara, J.; Yoshikawa, M. (1998). "Immunomodulatory activity of thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens". Bioorganic & Medicinal Chemistry Letters 8 (3): 215. doi:10.1016/S0960-894X(97)10221-9. 
Types of isocoumarins
Aglycones
Dihydroisocoumarins
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