Taspine
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| Taspine | ||
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| IUPAC name 1-[2-(Dimethylamino)ethyl]-3,8-dimethoxychromeno[5,4,3-cde]chromene-5,10-dione | ||
| Other names Thaspine | ||
| Identifiers | ||
| PubChem | 215159 | |
| Jmol-3D images | Image 1 | |
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| Properties | ||
| Molecular formula | C20H19NO6 | |
| Molar mass | 369.4 g/mol | |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa) | ||
| Infobox references | ||
Taspine is an alkaloid which acts as a potent acetylcholinesterase inhibitor and cicatrizant. It is found in various plants including Magnolia × soulangeana[1] and Croton lechleri.[2]
References
- ↑ Rollinger, JM; Schuster, D; Baier, E; Ellmerer, EP; Langer, T; Stuppner, H (2006). "Taspine: Bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana". Journal of Natural Products 69 (9): 1341–1346. doi:10.1021/np060268p. PMID 16989531.
- ↑ Vaisberg, A.; Milla, M.; Planas, M.; Cordova, J.; De Agusti, E.; Ferreyra, R.; Mustiga, M.; Carlin, L.; Hammond, G. (2007). "Taspine is the Cicatrizant Principle in Sangre de Grado Extracted from Croton lechleri". Planta Medica 55 (2): 140–143. doi:10.1055/s-2006-961907. PMID 2748730.
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