TRPC3
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Transient receptor potential cation channel, subfamily C, member 3 | |||||||||||||
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Identifiers | |||||||||||||
Symbols | TRPC3; TRP3 | ||||||||||||
External IDs | OMIM: 602345 MGI: 109526 HomoloGene: 20708 IUPHAR: TRPC3 GeneCards: TRPC3 Gene | ||||||||||||
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RNA expression pattern | |||||||||||||
More reference expression data | |||||||||||||
Orthologs | |||||||||||||
Species | Human | Mouse | |||||||||||
Entrez | 7222 | 22065 | |||||||||||
Ensembl | ENSG00000138741 | ENSMUSG00000027716 | |||||||||||
UniProt | Q13507 | B1ATV3 | |||||||||||
RefSeq (mRNA) | NM_001130698 | NM_019510 | |||||||||||
RefSeq (protein) | NP_001124170 | NP_062383 | |||||||||||
Location (UCSC) | Chr 4: 122.8 – 122.87 Mb | Chr 3: 36.62 – 36.69 Mb | |||||||||||
PubMed search | |||||||||||||
Transient receptor potential cation channel, subfamily C, member 3, also known as TRPC3, is a human gene encoding a protein of the same name.
Interactions
TRPC3 has been shown to interact with TRPC1[1][2] and TRPC6.[3]
See also
Further reading
- Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6.
- Lemmon MA (2005). "Pleckstrin homology domains: two halves make a hole?". Cell 120 (5): 574–6. doi:10.1016/j.cell.2005.02.023. PMID 15766521.
- Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100.
- Eder P, Poteser M, Groschner K (2007). TRPC3: A Multifunctional, Pore-Forming Signalling Molecule. "TRPC3: a multifunctional, pore-forming signalling molecule.". Handb Exp Pharmacol. Handbook of Experimental Pharmacology 179 (179): 77–92. doi:10.1007/978-3-540-34891-7_4. ISBN 978-3-540-34889-4. PMID 17217051.Eur J Neurosci. 2010 Apr;31(7):1219-32. Epub 2010 Mar 19.
References
- ↑ Strübing, Carsten; Krapivinsky Grigory, Krapivinsky Luba, Clapham David E (Oct 2003). "Formation of novel TRPC channels by complex subunit interactions in embryonic brain". J. Biol. Chem. (United States) 278 (40): 39014–9. doi:10.1074/jbc.M306705200. ISSN 0021-9258. PMID 12857742.
- ↑ Xu, X Z; Li H S, Guggino W B, Montell C (Jun 1997). "Coassembly of TRP and TRPL produces a distinct store-operated conductance". Cell (UNITED STATES) 89 (7): 1155–64. doi:10.1016/S0092-8674(00)80302-5. ISSN 0092-8674. PMID 9215637.
- ↑ Hofmann, Thomas; Schaefer Michael, Schultz Günter, Gudermann Thomas (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proc. Natl. Acad. Sci. U.S.A. (United States) 99 (11): 7461–6. doi:10.1073/pnas.102596199. ISSN 0027-8424. PMC 124253. PMID 12032305.
External links
- TRPC3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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