TRIM9

From Wikipedia, the free encyclopedia
Tripartite motif containing 9

PDB rendering based on 2db8.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsTRIM9; RNF91; SPRING
External IDsOMIM: 606555 MGI: 2137354 HomoloGene: 9045 GeneCards: TRIM9 Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez11408894090
EnsemblENSG00000100505ENSMUSG00000021071
UniProtQ9C026Q8C7M3
RefSeq (mRNA)NM_015163NM_001110202
RefSeq (protein)NP_055978NP_001103672
Location (UCSC)Chr 14:
51.44 – 51.56 Mb
Chr 12:
70.24 – 70.35 Mb
PubMed search

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[1][2][3]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[3]

Interactions

TRIM9 has been shown to interact with SNAP-25.[2]

References

  1. Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580. 
  2. 2.0 2.1 Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem 276 (44): 40824–33. doi:10.1074/jbc.M106141200. PMID 11524423. 
  3. 3.0 3.1 "Entrez Gene: TRIM9 tripartite motif-containing 9". 

Further reading

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