TGM4
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| Transglutaminase 4 (prostate) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | TGM4; TGP; hTGP | ||||||||||||
| External IDs | OMIM: 600585 MGI: 3027002 HomoloGene: 20689 ChEMBL: 3362 GeneCards: TGM4 Gene | ||||||||||||
| EC number | 2.3.2.13 | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 7047 | 331046 | |||||||||||
| Ensembl | ENSG00000163810 | ENSMUSG00000025787 | |||||||||||
| UniProt | P49221 | Q8BZH1 | |||||||||||
| RefSeq (mRNA) | NM_003241 | NM_177911 | |||||||||||
| RefSeq (protein) | NP_003232 | NP_808579 | |||||||||||
| Location (UCSC) | Chr 3: 44.92 – 44.96 Mb | Chr 9: 123.03 – 123.07 Mb | |||||||||||
| PubMed search | |||||||||||||
Protein-glutamine gamma-glutamyltransferase 4 is an enzyme that in humans is encoded by the TGM4 gene.[1][2][3]
References
- ↑ Gentile V, Grant FJ, Porta R, Baldini A (Oct 1995). "Localization of the human prostate transglutaminase (type IV) gene (TGM4) to chromosome 3p21.33-p22 by fluorescence in situ hybridization". Genomics 27 (1): 219–20. doi:10.1006/geno.1995.1032. PMID 7665178.
- ↑ Grant FJ, Taylor DA, Sheppard PO, Mathewes SL, Lint W, Vanaja E, Bishop PD, O'Hara PJ (Oct 1994). "Molecular cloning and characterization of a novel transglutaminase cDNA from a human prostate cDNA library". Biochem Biophys Res Commun 203 (2): 1117–23. doi:10.1006/bbrc.1994.2298. PMID 7916568.
- ↑ "Entrez Gene: TGM4 transglutaminase 4 (prostate)".
Further reading
- Davies G, Ablin RJ, Mason MD, Jiang WG (2007). "Expression of the prostate transglutaminase (TGase-4) in prostate cancer cells and its impact on the invasiveness of prostate cancer.". J. Exp. Ther. Oncol. 6 (3): 257–64. PMID 17552366.
- Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Dubbink HJ, de Waal L, van Haperen R, et al. (1998). "The human prostate-specific transglutaminase gene (TGM4): genomic organization, tissue-specific expression, and promoter characterization". Genomics 51 (3): 434–44. doi:10.1006/geno.1998.5393. PMID 9721214.
- Dubbink HJ, Verkaik NS, Faber PW, et al. (1996). "Tissue specific and androgen-regulated expression of human prostate-specific transglutaminase". Biochem. J. 315 ( Pt 3) (Pt 3): 901–8. PMC 1217292. PMID 8645175.
- Amendola A, Lombardi G, Oliverio S, et al. (1994). "HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by 'tissue' transglutaminase expression and prevented by cyclosporin A". FEBS Lett. 339 (3): 258–64. doi:10.1016/0014-5793(94)80427-3. PMID 7906657.
- Mariniello L, Esposito C, Di Pierro P, et al. (1993). "Human-immunodeficiency-virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro". Eur. J. Biochem. 215 (1): 99–104. doi:10.1111/j.1432-1033.1993.tb18011.x. PMID 7688299.
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