TERF2IP

From Wikipedia, the free encyclopedia
Telomeric repeat binding factor 2, interacting protein

PDB rendering based on 1fex.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsTERF2IP; DRIP5; RAP1
External IDsOMIM: 605061 MGI: 1929871 HomoloGene: 10357 GeneCards: TERF2IP Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez5438657321
EnsemblENSG00000166848ENSMUSG00000033430
UniProtQ9NYB0Q91VL8
RefSeq (mRNA)NM_018975NM_020584
RefSeq (protein)NP_061848NP_065609
Location (UCSC)Chr 16:
75.68 – 75.8 Mb
Chr 8:
112.01 – 112.02 Mb
PubMed search

Telomeric repeat-binding factor 2-interacting protein 1 is a protein that in humans is encoded by the TERF2IP gene.[1][2]

Interactions

TERF2IP has been shown to interact with Ku80,[3] Rad50[3] and TERF2.[1][3][4]

References

  1. 1.0 1.1 Li B, Oestreich S, de Lange T (July 2000). "Identification of human Rap1: implications for telomere evolution". Cell 101 (5): 471–83. doi:10.1016/S0092-8674(00)80858-2. PMID 10850490. 
  2. "Entrez Gene: TERF2IP telomeric repeat binding factor 2, interacting protein". 
  3. 3.0 3.1 3.2 O'Connor, Matthew S; Safari Amin, Liu Dan, Qin Jun, Songyang Zhou (July 2004). "The human Rap1 protein complex and modulation of telomere length". J. Biol. Chem. (United States) 279 (27): 28585–91. doi:10.1074/jbc.M312913200. ISSN 0021-9258. PMID 15100233. 
  4. Zhu, X D; Küster B, Mann M, Petrini J H, de Lange T (July 2000). "Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres". Nat. Genet. (UNITED STATES) 25 (3): 347–52. doi:10.1038/77139. ISSN 1061-4036. PMID 10888888. 

Further reading


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