Sulprostone

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Sulprostone

Systematic (IUPAC) name
(Z)-7-[(1R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	?
Identifiers
CAS number	60325-46-4^Y
ATC code	G02AD05
PubChem	CID 6917982
UNII	501Q5EQ1GM^Y
KEGG	D02725^Y
ChEMBL	CHEMBL284178^Y
Chemical data
Formula	C₂₃H₃₁N O₇S
Mol. mass	465.56 g/mol
SMILES O=S(=O)(NC(=O)CCC/C=C\C[C@H]2C(=O)C[C@@H](O)C2/C=C/[C@@H](O)COc1ccccc1)C
InChI InChI=InChI=1S/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/b7-2-,14-13+/t17-,19-,20?,22-/m1/s1 Key:UQZVCDCIMBLVNR-ZKLHUXKSSA-N
Y (what is this?) (verify)

Sulprostone is an oxytocic.

It is an analogue of prostaglandin E2.^[1]

References

Ergot alkaloids	Ergometrine^# (+oxytocin) Methylergometrine

Prostaglandins and analogues	E: Misoprostol/E1^# Gemeprost/E1 Dinoprostone/E2 Sulprostone/E2 F: Dinoprost/F2α Carboprost/F2α

Contraction induction

phys/devp/memb

mthr/fetu/infc, epon

proc, drug (2A/G2C)

Precursor

Precursor

Active

D/J	D₂

E/F	E₂ (Dinoprostone): Enprostil Sulprostone E₁ (Alprostadil): Misoprostol Gemeprost F_2α (Dinoprost): Bimatoprost Carboprost Latanoprost Tafluprost Travoprost Unoprostone

I	I₂ (Prostacyclin/Epoprostenol): Beraprost Iloprost Treprostinil

Precursor	Arachidonic acid 5-hydroperoxide

Initial	A₄ B₄

SRS-A	C₄ D₄ E₄

By function

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m (A16/C10), i (k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

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