Stephen Friend
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Stephen Friend at NightScience 2013 in Paris
Stephen H. Friend MD PhD is the president, co-founder and director of Sage Bionetworks.[1][2][3]
Formerly Senior Vice-President at Merck & Co. Friend co-founded Rosetta Inpharmatics with Leland H. Hartwell and Leroy Hood in 1996.[4] Much of his research has focused on cancer.[5]
Friend has also held faculty positions at Harvard Medical School and at Massachusetts General Hospital. He received his Bachelor of Arts in philosophy, his Ph.D. in biochemistry and his M.D. from Indiana University.[2]
Recognition
Friend is named an Ashoka Fellow by Ashoka: Innovators for the Public.[6]
Selected bibliography
- Bartz, S. R.; Zhang, Z.; Burchard, J.; Imakura, M.; Martin, M.; Palmieri, A.; Needham, R.; Guo, J.; Gordon, M.; Chung, N.; Warrener, P.; Jackson, A. L.; Carleton, M.; Oatley, M.; Locco, L.; Santini, F.; Smith, T.; Kunapuli, P.; Ferrer, M.; Strulovici, B.; Friend, S. H.; Linsley, P. S. (2006). "Small Interfering RNA Screens Reveal Enhanced Cisplatin Cytotoxicity in Tumor Cells Having both BRCA Network and TP53 Disruptions". Molecular and Cellular Biology 26 (24): 9377–9386. doi:10.1128/MCB.01229-06. PMC 1698535. PMID 17000754.
- Radich, J. P.; Dai, H.; Mao, M.; Oehler, V.; Schelter, J.; Druker, B.; Sawyers, C.; Shah, N.; Stock, W.; Willman, C. L.; Friend, S.; Linsley, P. S. (2006). "Gene expression changes associated with progression and response in chronic myeloid leukemia". Proceedings of the National Academy of Sciences 103 (8): 2794–2799. doi:10.1073/pnas.0510423103. PMC 1413797. PMID 16477019.
- Dai, H.; Van't Veer, L.; Lamb, J.; He, Y. D.; Mao, M.; Fine, B. M.; Bernards, R.; Van De Vijver, M.; Deutsch, P.; Sachs, A.; Stoughton, R.; Friend, S. (2005). "A Cell Proliferation Signature is a Marker of Extremely Poor Outcome in a Subpopulation of Breast Cancer Patients". Cancer Research 65 (10): 4059–4066. doi:10.1158/0008-5472.CAN-04-3953. PMID 15899795.
- Lampe, J. W.; Stepaniants, S. B.; Mao, M.; Radich, J. P.; Dai, H.; Linsley, P. S.; Friend, S. H.; Potter, J. D. (2004). "Signatures of environmental exposures using peripheral leukocyte gene expression: Tobacco smoke". Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 13 (3): 445–453. PMID 15006922.
- Van 't Veer, L. J.; Dai, H.; Van De Vijver, M. J.; He, Y. D.; Hart, A. A.; Bernards, R.; Friend, S. H. (2003). "Expression profiling predicts outcome in breast cancer". Breast cancer research : BCR 5 (1): 57–58. doi:10.1186/bcr562. PMC 154139. PMID 12559048.
- Van De Vijver, M. J.; He, Y. D.; Van't Veer, L. J.; Dai, H.; Hart, A. A. M.; Voskuil, D. W.; Schreiber, G. J.; Peterse, J. L.; Roberts, C.; Marton, M. J.; Parrish, M.; Atsma, D.; Witteveen, A.; Glas, A.; Delahaye, L.; Van Der Velde, T.; Bartelink, H.; Rodenhuis, S.; Rutgers, E. T.; Friend, S. H.; Bernards, R. (2002). "A Gene-Expression Signature as a Predictor of Survival in Breast Cancer". New England Journal of Medicine 347 (25): 1999–2009. doi:10.1056/NEJMoa021967. PMID 12490681.
- Lamb, J. R.; Zhang, C.; Xie, T.; Wang, K.; Zhang, B.; Hao, K.; Chudin, E.; Fraser, H. B.; Millstein, J.; Ferguson, M.; Suver, C.; Ivanovska, I.; Scott, M.; Philippar, U.; Bansal, D.; Zhang, Z.; Burchard, J.; Smith, R.; Greenawalt, D.; Cleary, M.; Derry, J.; Loboda, A.; Watters, J.; Poon, R. T.; Fan, S. T.; Yeung, C.; Lee, N. P.; Guinney, J.; Molony, C.; Emilsson, V. (2011). "Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting". In Wang, Xin Wei. PLoS ONE 6 (7): e20090. doi:10.1371/journal.pone.0020090. PMC 3130029. PMID 21750698.
- Mihich, E.; Feunteun, J.; Friend, S. (2002). "Thirteenth annual pezcoller symposium: Focusing analytical tools on complexity in cancer". Cancer Research 62 (13): 3883–3887. PMID 12097304.
References
- ↑ Kaiser, Jocelyn (2012). "Profile Stephen Friend: The Visionary". Science 335 (6069): 651–653. doi:10.1126/science.335.6069.651. PMID 22323794.
- ↑ 2.0 2.1 "Sage Bionetworks Seattle | Directors". Archived from the original on 2012-02-11.
- ↑ Anon (2008). "Stephen Friend". Nature Reviews Drug Discovery 7 (2): 114. doi:10.1038/nrd2509.
- ↑ Nelson, B.; Schadt, E. (2009). "Something wiki this way comes: Stephen Friend and Eric Schadt reveal their vision for an open-access platform in medical research.". Nature 458 (7234): 13. doi:10.1038/458013a. PMID 19262635.
- ↑ Kaiser, Jocelyn (2012). "Profile Stephen Friend: The Visionary". Science 335 (6069): 651–653. doi:10.1126/science.335.6069.651. PMID 22323794.
- ↑ http://sagebase.org/info/NewsInfoDownloads/SageAshokaRelease6APR2011.pdf
External links
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