Sofalcone

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Sofalcone

Systematic (IUPAC) name
[5-[(3-methylbut-2-en-1-yl)oxy]-2-((2E)-3-{4-[(3-methylbut-2-en-1-yl)oxy]phenyl}prop-2-enoyl)phenoxy]acetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	64506-49-6
ATC code	None
PubChem	CID 5282219
UNII	2B668TJX8E^Y
KEGG	D01956^Y
Chemical data
Formula	C₂₇H₃₀O₆
Mol. mass	450.52 g/mol
SMILES CC(=CCOC1=CC=C(C=C1)C=CC(=O)C2=C(C=C(C=C2)OCC=C(C)C)OCC(=O)O)C
Y (what is this?) (verify)

Sofalcone (INN) is an oral gastrointestinal medication. It is a synthetic derivative of sophoradin,^[1] a chalconoid, a type of natural phenol found in Sophora tonkinensis (or Sophora subprostrata), a herb used in traditional Chinese medicine.

References

↑ Konturek SJ, Mrzozowski T, Drozdowicz D, Pawlik W, Sendur R (August 1987). "Gastroprotective and ulcer healing effects of solon, a synthetic flavonoid derivative of sophoradin". Hepatogastroenterology 34 (4): 164–70. PMID 3478294.

Other

anat (t, g, p)/phys/devp/enzy

noco/cong/tumr, sysi/epon

proc, drug (A2A/2B/3/4/5/6/7/14/16), blte

v t e Chalconoids and their glycosides

Chalconoids	Butein Isoliquiritigenin Methyl hydroxychalcone Okanin

Chalconoid glycosides	Carthamin Marein okanin 3,4,3′-trimethyl ether 4′-glucoside okanin 4-methyl ether 4′-glucoside okanin 4-methyl ether 4′-glucoside monoacetate Okanin 3,4-dimethyl ether 4′-glucoside

Acetylated chalconoids	Licochalcone A Sophoradin (prenylated) Tephrospinosin (3′,5′-diisopentenyl-2′,4′-dihydroxychalcone) (prenylated) Xanthohumol (prenylated)

O-methylated chalconoids	Cardamomin Okanin 3,4,3′,4′-tetramethyl ether

Flavokavains	Flavokavain A Flavokavain B Flavokavain C

Synthetic	Sofalcone

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