Shikimate O-hydroxycinnamoyltransferase

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shikimate O-hydroxycinnamoyltransferase
Identifiers
EC number 2.3.1.133
CAS number 73904-44-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a shikimate O-hydroxycinnamoyltransferase (EC 2.3.1.133) is an enzyme that catalyzes the chemical reaction

4-coumaroyl-CoA + shikimate \rightleftharpoons CoA + 4-coumaroylshikimate

Thus, the two substrates of this enzyme are 4-coumaroyl-CoA and shikimate, whereas its two products are CoA and 4-coumaroylshikimate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 4-coumaroyl-CoA:shikimate O-(hydroxycinnamoyl)transferase. This enzyme is also called shikimate hydroxycinnamoyltransferase. This enzyme participates in phenylpropanoid biosynthesis.

References

    • Strack D, Keller H and Weissenbock G (1987). "Enzymatic-synthesis of hydroxycinnamic acid-esters of sugar acids and hydroaromatic acids by protein preparations from rye (Secale cereale) primary leaves". J. Plant Physiol. 131: 6173. 
    • Ulbrich B and Zenk MH (1980). "Partial purification and properties of p-hydroxycinnamoyl-CoA:shikimate-p-hydroxycinnamoyl transferase from higher plants". Phytochemistry 19 (8): 16251629. doi:10.1016/S0031-9422(00)83782-6. 
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