Serinolamide A
From Wikipedia, the free encyclopedia
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| Systematic (IUPAC) name | |
| (R,E)-N-(1-hydroxy-3-methoxypropan-2-yl)-N-methyloctadec-4-enamide | |
| Clinical data | |
| Legal status | ? |
| Identifiers | |
| ATC code | ? |
| PubChem | CID 56597771 |
| ChemSpider | 27025743 |
| Chemical data | |
| Formula | C23H45NO3 |
| Mol. mass | 383.61 g/mol |
| SMILES
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Serinolamide A is a naturally occurring eicosanoid derivative related to anandamide, which has been isolated from the marine cyanobacteria Lyngbya majuscula and related species in the Oscillatoria family. Testing established that serinolamide A is an active cannabinoid agonist with moderate potency, having a Ki of 1300nM at CB1 and 5x selectivity over the related CB2 receptor.[1]
See also
References
- ↑ Gutiérrez, M.; Pereira, A. R.; Debonsi, H. M.; Ligresti, A.; Di Marzo, V.; Gerwick, W. H. (2011). "Cannabinomimetic Lipid from a Marine Cyanobacterium". Journal of Natural Products 74 (10): 2313–2317. doi:10.1021/np200610t. PMC 3325759. PMID 21999614.
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