SYT9
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| Synaptotagmin IX | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SYT9; FLJ45896 | ||||||||||||
| External IDs | OMIM: 613528 MGI: 1926373 HomoloGene: 11062 GeneCards: SYT9 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 143425 | 60510 | |||||||||||
| Ensembl | ENSG00000170743 | ENSMUSG00000062542 | |||||||||||
| UniProt | Q86SS6 | Q9R0N9 | |||||||||||
| RefSeq (mRNA) | NM_175733 | NM_021889 | |||||||||||
| RefSeq (protein) | NP_783860 | NP_068689 | |||||||||||
| Location (UCSC) | Chr 11: 7.26 – 7.49 Mb | Chr 7: 107.37 – 107.55 Mb | |||||||||||
| PubMed search | |||||||||||||
Synaptotagmin-9 is a protein that in humans is encoded by the SYT9 gene.[1][2]
Interactions
SYT9 has been shown to interact with SYNCRIP,[3] TUBB[4] and TRPV1.[5]
References
- ↑ Craxton M (September 2001). "Genomic analysis of synaptotagmin genes". Genomics 77 (1–2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631.
- ↑ "Entrez Gene: SYT9 synaptotagmin IX".
- ↑ Mizutani, A; Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". J. Biol. Chem. (UNITED STATES) 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. ISSN 0021-9258. PMID 10734137.
- ↑ Haberman, Yael; Grimberg Elena, Fukuda Mitsunori, Sagi-Eisenberg Ronit (November 2003). "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules". J. Cell. Sci. (England) 116 (Pt 21): 4307–18. doi:10.1242/jcs.00719. ISSN 0021-9533. PMID 12966166.
- ↑ Morenilla-Palao, Cruz; Planells-Cases Rosa, García-Sanz Nuria, Ferrer-Montiel Antonio (June 2004). "Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity". J. Biol. Chem. (United States) 279 (24): 25665–72. doi:10.1074/jbc.M311515200. ISSN 0021-9258. PMID 15066994.
Further reading
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A (2004). "Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity". J. Biol. Chem. 279 (24): 25665–72. doi:10.1074/jbc.M311515200. PMID 15066994.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Haberman Y, Grimberg E, Fukuda M, Sagi-Eisenberg R (2004). "Synaptotagmin IX, a possible linker between the perinuclear endocytic recycling compartment and the microtubules". J. Cell. Sci. 116 (Pt 21): 4307–18. doi:10.1242/jcs.00719. PMID 12966166.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Dubois T, Howell S, Zemlickova E, Aitken A (2002). "Identification of casein kinase Ialpha interacting protein partners". FEBS Lett. 517 (1–3): 167–71. doi:10.1016/S0014-5793(02)02614-5. PMID 12062430.
- Zhang X, Kim-Miller MJ, Fukuda M, et al. (2002). "Ca2+-dependent synaptotagmin binding to SNAP-25 is essential for Ca2+-triggered exocytosis". Neuron 34 (4): 599–611. doi:10.1016/S0896-6273(02)00671-2. PMID 12062043.
- Fukuda M, Kowalchyk JA, Zhang X, et al. (2002). "Synaptotagmin IX regulates Ca2+-dependent secretion in PC12 cells". J. Biol. Chem. 277 (7): 4601–4. doi:10.1074/jbc.C100588200. PMID 11751925.
- Mizutani A, Fukuda M, Ibata K, et al. (2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". J. Biol. Chem. 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137.
- Perin MS (1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin". Biochemistry 35 (43): 13808–16. doi:10.1021/bi960853x. PMID 8901523.
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