SYT4
From Wikipedia, the free encyclopedia
Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene.[1][2]
References
Further reading
- Ullrich B, Li C, Zhang JZ, et al. (1995). "Functional properties of multiple synaptotagmins in brain.". Neuron 13 (6): 1281–91. doi:10.1016/0896-6273(94)90415-4. PMID 7993622.
- Perin MS (1996). "Mirror image motifs mediate the interaction of the COOH terminus of multiple synaptotagmins with the neurexins and calmodulin.". Biochemistry 35 (43): 13808–16. doi:10.1021/bi960853x. PMID 8901523.
- Thomas DM, Ferguson GD, Herschman HR, Elferink LA (1999). "Functional and biochemical analysis of the C2 domains of synaptotagmin IV.". Mol. Biol. Cell 10 (7): 2285–95. PMC 25443. PMID 10397765.
- Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
- Mizutani A, Fukuda M, Ibata K, et al. (2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.". J. Biol. Chem. 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137.
- Ferguson GD, Chen XN, Korenberg JR, Herschman HR (2001). "The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity.". J. Biol. Chem. 275 (47): 36920–6. doi:10.1074/jbc.M005801200. PMID 10938284.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
PDB gallery |
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| 1ugk: Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342) |
| 1w15: RAT SYNAPTOTAGMIN 4 C2B DOMAIN IN THE PRESENCE OF CALCIUM |
| 1w16: RAT SYNAPTOTAGMIN 4 C2B DOMAIN IN THE ABSENCE OF CALCIUM |
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| | Synaptic vesicle |
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| | COPI | |
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| | COPII | |
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| | RME/Clathrin | |
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| | Caveolae | |
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| | Other/ungrouped |
| Vesicle formation |
| Adaptor protein complex 1: | |
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| | Adaptor protein complex 2: | |
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| | Adaptor protein complex 3: | |
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| | Adaptor protein complex 4: | |
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| | | | | | | | BLOC-2: | |
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| | BLOC-3: | |
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| | Coats: | |
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| | Small GTPase | |
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| | Other | |
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see also vesicular transport protein disorders
B memb: cead, trns (1A, 1C, 1F, 2A, 3A1, 3A2-3, 3D), other |
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