SYNCRIP

From Wikipedia, the free encyclopedia
Synaptotagmin binding, cytoplasmic RNA interacting protein

PDB rendering based on 2dgu.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
SymbolsSYNCRIP; GRY-RBP; GRYRBP; HNRPQ1; NSAP1; PP68; hnRNP-Q
External IDsMGI: 1891690 HomoloGene: 4648 GeneCards: SYNCRIP Gene
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez1049256403
EnsemblENSG00000135316ENSMUSG00000032423
UniProtO60506Q7TMK9
RefSeq (mRNA)NM_001159673NM_019666
RefSeq (protein)NP_001153145NP_062640
Location (UCSC)Chr 6:
86.27 – 86.35 Mb
Chr 9:
88.45 – 88.48 Mb
PubMed search

Heterogeneous nuclear ribonucleoprotein Q is a protein that in humans is encoded by the SYNCRIP gene.[1][2][3]

Interactions

SYNCRIP has been shown to interact with ACF,[2][4] APOBEC1,[2] SYT7[5] and SYT9,[5]

References

  1. Harris CE, Boden RA, Astell CR (January 1999). "A novel heterogeneous nuclear ribonucleoprotein-like protein interacts with NS1 of the minute virus of mice". J Virol 73 (1): 72–80. PMC 103810. PMID 9847309. 
  2. 2.0 2.1 2.2 Lau PP, Chang BH, Chan L (May 2001). "Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome". Biochem Biophys Res Commun 282 (4): 977–83. doi:10.1006/bbrc.2001.4679. PMID 11352648. 
  3. "Entrez Gene: SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein". 
  4. Blanc, V; Navaratnam N, Henderson J O, Anant S, Kennedy S, Jarmuz A, Scott J, Davidson N O (March 2001). "Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing". J. Biol. Chem. (United States) 276 (13): 10272–83. doi:10.1074/jbc.M006435200. ISSN 0021-9258. PMID 11134005. 
  5. 5.0 5.1 Mizutani, A; Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". J. Biol. Chem. (UNITED STATES) 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. ISSN 0021-9258. PMID 10734137. 

Further reading


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