SLC9A5
From Wikipedia, the free encyclopedia
| Solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SLC9A5; NHE5 | ||||||||||||
| External IDs | OMIM: 600477 MGI: 2685542 HomoloGene: 31247 ChEMBL: 3058 GeneCards: SLC9A5 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 6553 | 277973 | |||||||||||
| Ensembl | ENSG00000135740 | ENSMUSG00000014786 | |||||||||||
| UniProt | Q14940 | B2RXE2 | |||||||||||
| RefSeq (mRNA) | NM_004594 | NM_001081332 | |||||||||||
| RefSeq (protein) | NP_004585 | NP_001074801 | |||||||||||
| Location (UCSC) | Chr 16: 67.27 – 67.31 Mb | Chr 8: 105.35 – 105.37 Mb | |||||||||||
| PubMed search | |||||||||||||
Sodium–hydrogen exchanger 5 is a protein that in humans is encoded by the SLC9A5 gene.[1][2][3]
See also
References
- ↑ Klanke CA, Su YR, Callen DF, Wang Z, Meneton P, Baird N, Kandasamy RA, Orlowski J, Otterud BE, Leppert M, et al. (Jun 1995). "Molecular cloning and physical and genetic mapping of a novel human Na+/H+ exchanger (NHE5/SLC9A5) to chromosome 16q22.1". Genomics 25 (3): 615–22. doi:10.1016/0888-7543(95)80002-4. PMID 7759094.
- ↑ Attaphitaya S, Park K, Melvin JE (Mar 1999). "Molecular cloning and functional expression of a rat Na+/H+ exchanger (NHE5) highly expressed in brain". J Biol Chem 274 (7): 4383–8. doi:10.1074/jbc.274.7.4383. PMID 9933642.
- ↑ "Entrez Gene: SLC9A5 solute carrier family 9 (sodium/hydrogen exchanger), member 5".
Further reading
- Baird NR, Orlowski J, Szabó EZ, et al. (1999). "Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain.". J. Biol. Chem. 274 (7): 4377–82. doi:10.1074/jbc.274.7.4377. PMID 9933641.
- Szaszi K, Paulsen A, Szabo EZ, et al. (2003). "Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton.". J. Biol. Chem. 277 (45): 42623–32. doi:10.1074/jbc.M206629200. PMID 12205089.
- Chagnon P, Michaud J, Mitchell G, et al. (2003). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis.". Am. J. Hum. Genet. 71 (6): 1443–9. doi:10.1086/344580. PMC 378590. PMID 12417987.
- Inoue H, Nakamura Y, Nagita M, et al. (2003). "Calcineurin homologous protein isoform 2 (CHP2), Na+/H+ exchangers-binding protein, is expressed in intestinal epithelium.". Biol. Pharm. Bull. 26 (2): 148–55. doi:10.1248/bpb.26.148. PMID 12576672.
- Lin WM, Chen XH, Xu R, et al. (2003). "[Tissue-specific expression of Na(+)-H(+) exchanger isoforms at two developmental stages of human fetus]". Sheng li xue bao : [Acta physiologica Sinica] 55 (1): 79–82. PMID 12598940.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Szabó EZ, Numata M, Lukashova V, et al. (2005). "beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform.". Proc. Natl. Acad. Sci. U.S.A. 102 (8): 2790–5. doi:10.1073/pnas.0407444102. PMC 549460. PMID 15699339.
- Onishi I, Lin PJ, Diering GH, et al. (2007). "RACK1 associates with NHE5 in focal adhesions and positively regulates the transporter activity.". Cell. Signal. 19 (1): 194–203. doi:10.1016/j.cellsig.2006.06.011. PMID 16920332.
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