SLC13A5
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| Solute carrier family 13 (sodium-dependent citrate transporter), member 5 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | SLC13A5; NACT | ||||||||||||
| External IDs | OMIM: 608305 HomoloGene: 21941 GeneCards: SLC13A5 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 284111 | 237831 | |||||||||||
| Ensembl | ENSG00000141485 | ENSMUSG00000020805 | |||||||||||
| UniProt | Q86YT5 | Q67BT3 | |||||||||||
| RefSeq (mRNA) | NM_001143838 | NM_001004148 | |||||||||||
| RefSeq (protein) | NP_001137310 | NP_001004148 | |||||||||||
| Location (UCSC) | Chr 17: 6.59 – 6.62 Mb | Chr 11: 72.24 – 72.27 Mb | |||||||||||
| PubMed search | |||||||||||||
Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter is a protein that in humans is encoded by the SLC13A5 gene.[1]
Function
SLC13A5 is a tricarboxylate plasma transporter with a preference for citrate.[1]
References
Further reading
- Pajor, A. M. (2005). "Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters". Pflügers Archiv - European Journal of Physiology 451 (5): 597–605. doi:10.1007/s00424-005-1487-2. PMC 1866268. PMID 16211368.
- Inoue, K.; Zhuang, L.; Ganapathy, V. (2002). "Human Na+ -coupled citrate transporter: Primary structure, genomic organization, and transport function". Biochemical and biophysical research communications 299 (3): 465–471. doi:10.1016/S0006-291X(02)02669-4. PMID 12445824.
- Gopal, E.; Miyauchi, S.; Martin, P. M.; Ananth, S.; Srinivas, S. R.; Smith, S. B.; Prasad, P. D.; Ganapathy, V. (2006). "Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines". AJP: Gastrointestinal and Liver Physiology 292 (1): G402–G408. doi:10.1152/ajpgi.00371.2006. PMID 16973915.
- Benjamin, D. J.; Cesarini, D.; Van Der Loos, M. J. H. M.; Dawes, C. T.; Koellinger, P. D.; Magnusson, P. K. E.; Chabris, C. F.; Conley, D.; Laibson, D.; Johannesson, M.; Visscher, P. M. (2012). "The genetic architecture of economic and political preferences". Proceedings of the National Academy of Sciences 109 (21): 8026–8031. doi:10.1073/pnas.1120666109. PMC 3361436. PMID 22566634.
- Inoue, K.; Zhuang, L.; Maddox, D. M.; Smith, S. B.; Ganapathy, V. (2003). "Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action". Biochemical Journal 374 (Pt 1): 21–26. doi:10.1042/BJ20030827. PMC 1223593. PMID 12826022.
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